A retinal ganglion cell (RGC) is a type of neuron located near the inner surface (the ganglion cell layer) of the retina of the eye. It receives visual information from photoreceptors via two intermediate neuron types: bipolar cells and retina amacrine cells.

It is a group of optic neuropathies characterized by the death of retinal ganglion cells (RGCs), leading to a specific deformation of the optic nerve head. Peripheral vision declines first in glaucoma, while central vision loss occurs much later.

Jan 18, 2018 · Retinal ganglion cells (RGCs) are particularly important in glaucoma because they are the cells that are damaged by the disease. The retina is a thin tissue in the back of the eye containing different kinds of nerve cells.

A retinal ganglion cell (RGC) is a type of neuron located near the inner surface (the ganglion cell layer) of the retina of the eye. It receives visual information from photoreceptors via two intermediate neuron types: bipolar cells and amacrine cells.

Intrinsically photosensitive retinal ganglion cells (ipRGCs), also called photosensitive retinal ganglion cells (pRGC), or melanopsin-containing retinal ganglion cells (mRGCs), are a type of neuron in the retina of the mammalian eye.

Aug 21, 2015 · It is caused by the progressive loss of retinal ganglion cells (RGCs), predominantly via apoptosis, within the retinal nerve fibre layer and the corresponding loss of axons of the optic nerve head....

Retinal ganglion cells (RGCs) are specialized projection neurons that relay an immense amount of visual information from the retina to the brain. RGC signal inputs are collected by dendrites and output is distributed from the cell body via very thin (0.5-1 μm) and long (∼50 mm) axons.

Jan 13, 2017 · Retinal ganglion cells (RGCs) provide the final common pathway to transmit all visual information processed by the retina to the brain.

Intrinsically photosensitive retinal ganglion cells (ipRGCs) are a relatively recently discovered novel class of photoreceptor in the vertebrate retina. The photopigment melanopsin confers photosensitivity upon these cells. ipRGCs mediate nonvisual effects of light. The anatomy, physiology, and function of these cells are described herein.

Implantable devices for sustained drug delivery are becoming a new wave of treatments for eye disease. Neurotech, the company that makes the NT-501 CNTF implant is also developing another product, NT-503, that is being evaluated for intraocular delivery of a VEGF receptor fusion protein for treatment of macular disease.