Helper virus-dependent replication-competent AAV (rcAAV), also known as "wild-type" or "pseudo-wild-type" AAV, is an AAV capsid particle containing AAV rep and cap flanked by …

Creative Biogene offers testing services for detection of rcAAV in compliance with FDA, ICH, and CPMP guidelines. We have established a method to detect rcAAV more sensitively and rapidly.

Cell Biolabs’ AAV Helper-Free System allows the production of infectious recombinant human adeno-associated virus (rAAV) virions without the use of a helper virus (Figure 2).

Apr 21, 2023 · In the present study, we established an AAV production system that regulates the timing of capsid expression using a tetracycline-dependent promoter. Tetracycline-regulating …

pPLUS ® AAV-RC range is a set of RepCap plasmids designed for AAV production of various serotypes. The plasmids have been optimized for use with pPLUS ® AAV-Helper in a triple …

Gene delivery vectors based on recombinant adeno-associated virus (AAV) are powerful tools for studying myogenesis in normal and diseased conditions. Strategies have been developed to …

Adeno-associated virus (AAV) vector preparations are often contaminated with variable amounts of replication-competent AAV (rcAAV), which may influence the behavior of these vectors both …

Sep 6, 2019 · The U.S. Navy and the Marine Corps Systems Command (MCSC) recently harnessed the power of unmanned technology and successfully tested the Remote Control …

Dec 4, 2017 · Recombinant adeno-associated viruses (rAAV) have gained increasing attention in the viral gene therapy field. A safe clinical profile, availability of viral serotypes with different …

To this end, a real-time quantitative polymerase chain reaction (qPCR) assay was developed to establish the amount of rcAAV or wtAAV present in rAAV stocks. An intact left AAV ITR- rep …