Nov 27, 2017 · R7 treatment activated PTEN and downregulated mTOR phosphorylation without affecting mTOR expression, though regulatory-associated protein of mTOR (raptor) …

Yamaha's proven 689cc twin-cylinder DOHC fuel-injected engine delivers excellent power and performance throughout the rpm range for an exhilarating ride and a true Supersport …

Feb 7, 2025 · To define the role of mTOR in driving resistance in our models, we targeted mTORC1 with RAD001 (100 nM, 4 hours) in combination with ipatasertib (500 nM, 4 hours) …

Nov 27, 2017 · R7 treatment activated PTEN and downregulated mTOR phosphorylation without affecting mTOR expression, though regulatory-associated protein of mTOR (raptor) …

Aug 19, 2022 · This review focuses on the structure of mTOR protein and related signaling pathways as well as the structure and characteristics of various mTOR inhibitors. Non-rapalog …

ICA and curcumol synergistically regulated the miR-7/mTOR/SREBP1 pathway to induce autophagy and ferroptosis in PCa cells and affected lipid metabolism. Keywords: ICA; …

These results indicate that R7 inhibits Akt and mTOR phosphorylation and activates PTEN. MTT and Annexin V-FITC/propidium iodide (PI) assay results showed that pretreatment with the …

Notoginsenoside R7 was isolated from Panax notoginseng, a plant used commonly in traditional Chinese medicine. We investigated the anti-cancer effects of R7 in HeLa cells in vitro and in …

Nov 27, 2017 · Our study suggests that R7 is a promising chemotherapeutic agent for the treatment of cervical cancer and other PI3K/PTEN/Akt/mTOR signaling-associated tumors. R7 …

Notoginsenoside R7 was isolated from Panax notoginseng, a plant used commonly in traditional Chinese medicine. We investigated the anti-cancer effects of R7 in HeLa cells in vitro and in …