Tyrosine-protein phosphatase non-receptor type 21 is an enzyme that in humans is encoded by the PTPN21 gene. [5][6] The protein encoded by this gene is a member of the protein tyrosine …

Mar 30, 2025 · PTPN21 (Protein Tyrosine Phosphatase Non-Receptor Type 21) is a Protein Coding gene. Diseases associated with PTPN21 include Prostate Cancer and Gastric …

Apr 4, 2019 · Knockout of Ptpn21 results in decreased cellular stiffness, enhanced deformability and motility, stem and progenitor cell egress, and defective hematopoietic reconstitution …

Apr 4, 2019 · Hematopoietic stem cell (HSC) quiescence is a tightly regulated process crucial for hematopoietic regeneration, which requires a healthy and supportive microenvironmental …

Feb 28, 2024 · PTPN21 belongs to the four-point-one, ezrin, radixin, moesin (FERM) domain–containing protein tyrosine phosphatases (PTP) and plays important roles in …

Feb 8, 2025 · PTPN21-CDSlong isoform inhibits the response of acute lymphoblastic leukemia cells to NK-mediated lysis via the KIR/HLA-I axis. Study demonstrates that PTPN21 activates …

Feb 8, 2025 · The FERM domain of Ptpn21 stimulates dense core vesicle transport in primary hippocampal neurons and rescues integrin trafficking in Kif1c-depleted cells. PTPD1 is a …

Mechanistically, Ptpn21 modulates cell mechanics by dephosphorylating Septin1 (Tyr246). Hematopoietic stem cell (HSC) quiescence is a tightly regulated process crucial for …

Nov 23, 2023 · PTPN21-CDS_long isoform inhibits the response of acute lymphoblastic leukemia cells to NK-mediated lysis via the KIR/HLA-I axis. Two non …

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