Proin, the short name for phenylpropanolamine (often abbreviated as PPA), is a popular prescription medication for urethral incontinence in dogs. Until recently, phenylpropanolamine for dogs was used as an off-label treatment for incontinence.

Dec 19, 2024 · Proin (phenylpropanolamine) is used to treat urinary incontinence in dogs. Use Proin with caution in dogs with preexisting conditions like heart disease or hypertension (high blood pressure). The dosage of Proin depends on whether you are using the immediate-release or extended-release formulation.

Indicated for the control of urinary incontinence due to urethral sphincter hypotonus in dogs. Federal law restricts this drug to use by or on the order of a licensed veterinarian. See full prescribing information for complete dosing and administration instructions. Active Ingredient (s): phenylpropanolamine hydrochloride.

Proin (PRN Pharmacal, prnpharmacal.com) is the only veterinary Food and Drug Administration (FDA)-approved phenylpropanolamine hydrochloride medication marketed in the United States to treat urinary incontinence due to hypotonicity of the urethral sphincter.

What is phenylpropanolamine? Phenylpropanolamine (brand names: Proin®, Propalin®, Cystolamine®, Uricon®, Uriflex-PT®) is a sympathomimetic medication used to treat urinary incontinence due to poor muscle tone in the urethral sphincter. Its use in cats and dogs at certain doses to treat urinary incontinence is ‘off label’ or ‘extra label’.

Feb 3, 2023 · Proin—a brand of phenylpropanolamine for dogs—is a popular prescription medication for urinary incontinence. While phenylpropanolamine—or PPA as it's sometimes known—was designed as a decongestant for humans, it is now sold in the United States for veterinary use only.

Proin is the best choice for a dogs suffering from urinary incontinence. These chewable tablets use phenylpropanolamine, an FDA-approved ingredient that treats and manages urinary incontinence in canines. This adrenergic agent works by tightening the sphincter muscle of the bladder, which helps the dog control leakage.

Dec 8, 2022 · Proin ® treats urinary incontinence by stimulating the smooth muscles of the urethra, bladder neck, and urethral sphincter to increase tone and closing the neck of the bladder. Please follow the directions on the drug label for Proin ® …

Mar 2, 2025 · INDICATION: For the control of urinary incontinence due to urethral sphincter hypotonus in dogs. The recommended dosage is 2 to 4 mg/kg (0.9 to 1.8 mg/lb) of body weight once daily according to Table 1 below. Administer PROIN ER with food (see Clinical Pharmacology). Do not split or crush tablets.