Meng How’s overall research goal is to advance the field of nucleic acid editing. His lab seeks to (1) develop new genome and transcriptome engineering tools, including CRISPR-based technologies, for synthetic biology applications, and (2) gain fundamental insights into the ADAR family of enzymes, which are essential proteins involved in RNA ...

Meng How Tan. Nanyang Technological University. Verified email at ntu.edu.sg - Homepage. RNA editing ADAR genome engineering CRISPR. Articles ... Cited by. Year; Dynamic landscape and regulation of RNA editing in mammals. MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017. 620: 2017: Accurate ...

We are focused on (1) developing and applying powerful new genome engineering technologies to understand cell fate decisions and (2) unraveling the functions and regulation of RNA editing in human development and diseases. Our research activities fall under the broad umbrella of systems and synthetic biology.

TAN Meng How Associate Professor Deputy Director (Undergraduate), Renaissance Engineering Programme

Dr. Meng How Tan received his B.S. degree in mechanical engineering and B.A. degree in economics from University of California - Berkeley, his M.S. degree in aeronautics from California Institute of Technology, his M.S. degree in biomedical engineeri ...

Sep 9, 2020 · Joining the global fight against COVID-19, Asst Prof Tan is using precision genome engineering, including CRISPR-Cas gene editing technology, to develop rapid diagnostic assays for SARS-CoV-2. Structure of CRISPR/Cas9 in complex with guide RNA (red) and DNA (yellow).

Oct 25, 2021 · This is what has brought Associate Professor Tan Meng How to where he is today – award-winning researcher and mentor to the next generation of engineers. When he was a child, he was fascinated by how planes could fly.

Oct 16, 2017 · Co-lead author of the study Prof Tan Meng How- together with his team has comprehensively profiled A-to-I editing in multiple human tissues and compared editing in humans to non-human primates and mice.

Meng How Tan is currently an Assistant Professor in the School of Chemical and Biomedical Engineering at Nanyang Technological University (NTU) as well as a Senior Research Scientist in the Genome Institute of Singapore at Agency for Science Technology and Research (A*STAR).

He leverages on cutting edge technologies, high throughput approaches, and engineering principles to investigate regulatory networks in biology. He studies both prokaryotes (e.g. bacteria) and eukaryotes (including human) and is interested in both …