PRKCD - Wikipedia
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by the second messenger diacylglycerol. [6] . PKC family members phosphorylate a …
PRKCD Gene - GeneCards | KPCD Protein | KPCD Antibody
Mar 30, 2025 · PRKCD (Protein Kinase C Delta) is a Protein Coding gene. Diseases associated with PRKCD include Autoimmune Lymphoproliferative Syndrome, Type Iii and Autoimmune …
Role of PRKDC in cancer initiation, progression, and treatment
Oct 26, 2021 · The PRKDC gene encodes the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) protein. DNA-PKcs plays an important role in nonhomologous end joining (NHEJ) …
PRKCD protein kinase C delta [ (human)] - National Center for ...
PRKCD-mediated CREB activation regulates ghrelin-induced COX 2 expression and dinoprostone production in colonic epithelial cells. Our results indicate that loss of PKC delta is an indicator …
B-cell deficiency and severe autoimmunity caused by deficiency …
Apr 18, 2013 · PRKCD deficiency causes a novel primary immunodeficiency with B-cell deficiency and severe autoimmunity. Protein kinase C δ may represent a key factor controlling immune …
GAK and PRKCD are positive regulators of PRKN-independent …
Oct 20, 2021 · We identify Cyclin G-associated kinase (GAK) and Protein Kinase C Delta (PRKCD) as regulators of PRKN-independent mitophagy, with both being dispensable for …
PRKCD protein kinase C delta - NIH Genetic Testing Registry …
Dec 10, 2024 · Clinical resource with information about PRKCD, Autoimmune lymphoproliferative syndrome, type III caused by mutation in PRKCD, Host-microbe interactions have shaped the …
Protein Kinase C δ: a Gatekeeper of Immune Homeostasis
Aug 19, 2016 · Recently, patients with autosomal recessive mutations in PRKCD encoding protein kinase c delta (PKCδ) have been identified, representing a monogenic prototype for one of the …
Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell ...
We identified a homozygous, loss-of-function mutation in PRKCD (PKCδ) in a patient who presented with chronic lymphadenopathy, splenomegaly, autoantibodies, elevated …
Entry - *176977 - PROTEIN KINASE C, DELTA; PRKCD - OMIM
Nov 8, 2021 · The PRKCD gene encodes a member of the protein kinase C family, members of which are critical for regulation of cell survival, proliferation, and apoptosis. In B lymphocytes, …