Pregnane, also known as 17β-ethylandrostane or as 10β,13β-dimethyl-17β-ethylgonane, is a C21 steroid and, indirectly, a parent of progesterone. It is a parent hydrocarbon for two series of steroids stemming from 5α-pregnane (originally allopregnane ) and …

Pregnane | C21H36 | CID 439513 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

A pregnane is a type of neurosteroid, such as AlloP, which is synthesized in the brain and acts as a positive allosteric modulator at GABA A receptors, influencing neuronal excitability and exhibiting various therapeutic effects in the nervous system.

4 days ago · The meaning of PREGNANE is a crystalline steroid C21H36 that is related to cholane and is the parent compound of the corticosteroid and progestational hormones.

Looking for online definition of pregnane in the Medical Dictionary? pregnane explanation free. What is pregnane? Meaning of pregnane medical term. What does pregnane mean?

Pregnane X receptor (PXR) is a pivotal nuclear receptor modulating xenobiotic metabolism primarily through its regulation of CYP3A4, the most important enzyme involved in drug metabolism in humans.

The pregnane X receptor (PXR, NR1I2) is a member of the nuclear receptor superfamily that is activated by a myriad of compounds and natural products in clinical use. Activation of PXR represents the basis for several clinically important drug–drug interactions.

Since world war II, pregnane derivatives (C-21 steroids) have acquired an unusual medical and social importance as hormonal agonists and antagonists, mainly due to the growing exposure of mankind to physical and psychological stress and the explosive increase of world population.

ChemSpider record containing structure, synonyms, properties, vendors and database links for Pregnane, 24909-91-9, JWMFYGXQPXQEEM-WZBAXQLOSA-N

Pregnane, also known as 17β-ethylandrostane or as 10β,13β-dimethyl-17β-ethylgonane, is a C21 steroid and, indirectly, a parent of progesterone. It is a parent hydrocarbon for two series of steroids stemming from 5α-pregnane (originally allopregnane) and 5β …