Memory impairment and cognitive decline are two of the greatest concerns with long-term administration of drugs that affect the CNS. In this study, we discovered a significant association between cumulative exposure to gabapentin and pregabalin and the risk of dementia.

Apr 17, 2023 · Today, gabapentinoids such as Gabapentin (GBP) and pregabalin (PGB) are widely used as painkillers. This may alter the function of the nervous system; hence their results may include a difference in memory and processes that end in memory formation.

Jul 3, 2024 · Memory loss and difficulty with concentration are both considered common side effects of Lyrica. Because Lyrica is used to treat severe, chronic pain, these side effects are often felt to be worth the risk.

Memory loss is reported as a side effect among people who take Pregabalin (pregabalin), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Pantoprazole, and have Neuralgia.

See what Pregabalin users say about memory loss. Out of 1668 reviews, 77 (4.6%) mention memory loss. Read firsthand experiences.

Mar 2, 2010 · At conventional doses and titration, pregabalin induced mild negative cognitive effects and neurotoxicity complaints in healthy volunteers. These effects are one factor to be considered in the selection and monitoring of chronic AED therapy.

Jan 23, 2025 · Among these, Lyrica (pregabalin) often emerges as a focal point due to its widespread use and reported effects on memory. This article aims to unravel the complexities surrounding Lyrica and its impact on memory, providing a comprehensive overview that balances scientific evidence with practical insights.

Mar 1, 2010 · Pregabalin is a relatively new AED widely used for the treatment of seizures and some types of chronic pain including fibromyalgia. We measured the cognitive effects of 12 weeks of pregabalin in healthy volunteers.

These results suggest that simultaneous administration of baclofen with gabapentin or pregabalin can cause memory deficits due to their additive effects in combination therapy on inhibition of excitatory neurotransmitters.

See what Lyrica users say about memory loss. Out of 925 reviews, 59 (6.4%) mention memory loss. Read firsthand experiences.