In organic chemistry, polyenes are poly-unsaturated, organic compounds that contain at least three alternating double (C=C) and single (C−C) carbon–carbon bonds. These carbon–carbon …

What are Polyenes? Antifungal agents are also called antimycotic agents. Polyene antifungals bind to ergosterol, the main sterol in the fungal cell membrane, and cause depolarization of the …

Polyenes are a group of antifungal drugs with multiple conjugated double bonds and a heavily hydroxylated region on the ring opposite to the conjugated system. These are amphiphilic and …

Polyunsaturated alkenes, or polyenes, are compounds that have several carbon-carbon double bonds. The double bonds can be spaced out along the carbon chain, with several carbon …

Polyene antimycotics, sometimes referred to as polyene antibiotics, are a class of antimicrobial polyene compounds that target fungi. [1] . These polyene antimycotics are typically obtained …

Polyenes are small pharmaceutical molecules that produce a great variety of phenomena on lipid membranes and biological cells, and many studies have sought to understanding the …

Jul 22, 2018 · Polyenes are formally defined as materials containing an even number of methyne (=CH–) groups covalently bonded to form a linear carbon chain bearing one p electron on …

Jan 12, 2021 · Polyenes were, after griseofulvin, the first fungal-specific antibiotics on the market and ever since, more than 200 polyene antifungals have been discovered, of which …

Discover the fascinating world of polyenes, a significant group of compounds in the field of microbiology. Unpack their definition, understand their structural formation, explore various …

Clinical information about amphotericin B, nystatin and natamycin. Mechanism, activity, side effects and toxicity, drug interactions.