BOX ligand complex enhances catalytic enantioselective aziridination of styrene, with phenyl substituents proving superior over t-Bu groups.

Bis(oxazoline) ligands (often abbreviated BOX ligands) are a class of privileged chiral ligands containing two oxazoline rings. They are typically C 2 ‑symmetric and exist in a wide variety of forms; with structures based around CH 2 or pyridine linkers being particularly common (often generalised BOX and PyBOX respectively).

Mar 1, 2008 · It is quite apparent that, the bis(oxazoline) ligand is even more strongly bent in this complex, caused by the six-membered palladacycle residing in a boat conformation. This is most likely a consequence of minimizing steric interactions of the phenyl group in the allyl ligand with the proximal benzyl group of the bis(oxazoline) ligand.

May 21, 2021 · Phosphinooxazoline (PHOX) is a popular class of bidentate ligand in which the chiral oxazoline moiety is solely responsible for asymmetric induction in product formation (Figure 2). (3−6) In this section, various PHOX ligands (1 – 17) and their applications in a broad range of asymmetric transformations will be discussed.

Sep 9, 2019 · In contrast to the rapid growth of synthetic electrochemistry in recent years, enantioselective catalytic methods powered by electricity remain rare. In this work, we report the development of a highly enantioselective method for the …

Jan 15, 2024 · The box ligand is (4S-+)-phenyl-α-[(4S)-phenyloxazolidin-2-ylidene]-2-oxazoline-2-acetonitrile. The emission of these complexes span across the visible and into the near-ultraviolet region of the electromagnetic spectrum with moderate to high photoluminescence quantum yields (Φ PL = 0.45–1.0).

Dec 17, 2022 · Chiral indane-derived bis(oxazoline) ligand (L17) bearing two pendent side arm groups was found to be the optimal ligand among a series of chiral BOX ligands.

In chemistry, bisoxazoline ligands (BOX ligands for short) are chiral ligands based on an bis oxazoline skeleton and used in combination with a metal compound in asymmetric synthesis as a chiral catalyst [1]. Three frequently encountered such ligands are PyBOX, tBuBOX and PhBOX.

Most important, the inclusion of alkyl groups atop the BOX ligand (as a sterically repulsive “hat” or “umbrella” for the Cu catalyst) was vital for high enantioselectivity. For example, a methyl (R = H, 38% ee) is not as effective as propyl (R = Et, 58% ee) or benzyl (R = Ph, 95% ee).

Jun 10, 2003 · Enantiopure Pyridine Bis(oxazoline) “Pybox” and Bis(oxazoline) “Box” Iron Dialkyl Complexes: Comparison to Bis(imino)pyridine Compounds and Application to Catalytic Hydrosilylation of Ketones.