Mar 1, 2015 · In summary, lung injury in emphysema results from complex interactions between diverse processes including inflammation, proteinases, oxidative stress and cellular death.

In summary, lung injury in emphysema results from complex interactions between diverse processes including inflammation, proteinases, oxidative stress and cellular death. While well described in mice, key cells and culprits in human disease are not as clear.

Jan 26, 2023 · Emphysema is a pathological diagnosis affecting the air spaces distal to the terminal bronchiole. It is characterized by abnormal permanent enlargement of lung air spaces with the destruction of their walls without any fibrosis and destruction of lung parenchyma with loss of elasticity.

Jan 2, 2019 · Pulmonary emphysema is part of pathological condition in chronic obstructive pulmonary disease (COPD) which is characterized by lung parenchymal destruction. Morphology classification of emphysema had been made according to histologic structure in pathology.

Mar 22, 2025 · Pulmonary emphysema is defined as the "abnormal permanent enlargement of the airspaces distal to the terminal bronchioles accompanied by destruction of the alveolar wall 1. The criteria "absence of obvious fibrosis" may not be necessary because interstitial fibrosis may be present in cigarette smokers' emphysematous lungs 13.

Identification of cellular and molecular mechanisms of COPD pathogenesis is an area of active, ongoing research that may help to determine therapeutic targets for emphysema. Keywords: emphysema, apoptosis, protease–antiprotease balance, oxidative stress, hypoxemia.

At any pleural pressure, the lung volume is higher than normal. Additionally, the altered relation between pleural and alveolar pressure facilitates expiratory dynamic compression of airways. Such compression limits airflow during forced expiration and, in …

Pulmonary emphysema is part of pathological condition in chronic obstructive pulmonary disease (COPD) which is characterized by lung parenchymal destruction. Morphology classification of emphysema had been made according to histologic structure in pathology.

Apr 26, 2024 · Emphysema is pathologically defined as an abnormal permanent enlargement of air spaces distal to the terminal bronchioles, accompanied by the destruction of alveolar walls and without obvious...

Sep 1, 1983 · Chronic airflow limitation is caused by a variety of disorders that can be difficult to distinguish clinically. Emphysema and chronic bronchitis are often considered together under the term "chronic obstructive pulmonary disease" (COPD).