Oct 13, 2022 · To overcome these limitations, we develop a new crosstalk-based PEA method, CTpathway, based on a global pathway crosstalk map (GPCM) with >440,000 edges by …

Biological crosstalk refers to instances in which one or more components of one signal transduction pathway affects another. This can be achieved through a number of ways with …

Cross-Talk between Pathways We have been representing the major signal transduction pathways as if they were linear chains, through which information flows in a single conduit. …

XTalkDB uses a biologically grounded principle to determine if there is crosstalk from one pathway (say, A) to another (say, B): an experiment demonstrates that perturbing at least one …

Visualize pathway crosstalk using interactive networks. Use as a gold standard for computational methods that detect whether pathways may crosstalk. Validate context-specific crosstalk using …

Pathway crosstalk is the phenomenon of pathway interaction or cooperation. The signal-inducing conditions such as environmental stimulations can activate different pathways by inducing …

Oct 13, 2022 · Methods: To overcome these limitations, we develop a new crosstalk-based PEA method, CTpathway, based on a global pathway crosstalk map (GPCM) with >440,000 edges …

Sep 23, 2015 · The Hippo pathway is known to crosstalk with the TGF-β pathway [see Varelas and Wrana (2012) for a review of Hippo signaling]. Evidence in the literature indicates two …

Oct 13, 2022 · CTpathway is an on-line crosstalk-based pathway enrichment analysis tool based on eight pathway databases. We support performing pathway enrichment analysis from KEGG …

Jan 4, 2017 · XTalkDB contains curated information for 650 pairs of pathways from over 1600 publications. In addition, the database reports the molecular components (e.g. proteins, …