Mar 30, 2025 · PSMA1 (Proteasome 20S Subunit Alpha 1) is a Protein Coding gene. Diseases associated with PSMA1 include Thyroid Hemiagenesis and Cystic Fibrosis. Among its related pathways are Autodegradation of the E3 ubiquitin ligase COP1 and CDK-mediated phosphorylation and removal of Cdc6.

Jun 25, 2024 · The PSMA PET scan is a type of positron emission tomography (PET) scan that uses a special dye with radioactive tracers that bind to prostate-specific membrane antigens (PSMA), a protein found...

A PSMA scan is a nuclear medicine imaging technique used in the diagnosis and staging of prostate cancer. It is carried out by injection of a radiopharmaceutical with a positron or gamma emitting radionuclide and a prostate-specific membrane antigen (PSMA) targeting ligand.

Prostate-specific membrane antigen (PSMA) is a type II membrane protein originally characterized by the murine monoclonal antibody (mAb) 7E11-C5.3 and is expressed in all forms of prostate tissue, including carcinoma. 1–6 The PSMA protein has a unique 3-part structure: a 19-amino-acid internal portion, a 24-amino-acid transmembrane portion, and ...

Jan 29, 2025 · In people who have an early recurrence of prostate cancer, a PSMA PET scan can detect PSA as low as 0.2 or 0.3 nanograms per milliliter (ng/mL). A nanogram is one-billionth of a gram, and a milliliter is 1/1,000 of a liter.

Nov 23, 2022 · We found that PSMA1 was upregulated in GC and promoted proliferation, migration and invasion in GC cells. Herein, we report transcriptional co-activator with PDZ-binding motif (TAZ) was a...

Mar 29, 2021 · Prostate-specific membrane antigen (PSMA) is a promising target for the treatment of advanced prostate cancer (PC) and various solid tumors.

Jul 8, 2024 · Prostate-specific membrane antigen (PSMA) is an important cell-surface imaging biomarker and therapeutic target in prostate cancer. The PSMA-targeted theranostic 177 Lu-PSMA-617 was...

Mar 27, 2025 · This was possible thanks to the specificity of PSMA for PCa: as extensively reported in literature, PSMA is a transmembrane protein that is significantly overexpressed in PCa cells compared with normal prostate tissue, making it an ideal molecular target for imaging [1], [2]. PSMA PET imaging involves the use of radiolabeled ligands, such as ...

Official gene symbol, which is typically a short form of the gene name, according to HGNC. Assigned HPA protein class (es) for the encoded protein (s). Number of protein-coding transcripts from the gene as defined by Ensembl.