Jan 28, 2025 · Primary sclerosing cholangitis (PSC) is an uncommon inflammatory condition that affects the biliary tree resulting in multiple strictures, liver damage, and eventually cirrhosis.

Although MRI/MRCP is the best noninvasive imaging modality for detecting developing CCA in PSC, it can still be a challenge and high-quality MRCP and reader experience are important to improve accuracy.

Magnetic resonance imaging (MRI)/magnetic resonance cholangiopancreatography (MRCP) are considered the imaging stan-dard for diagnosis and follow-up in patients with PSC. Currently, there are no universally accepted reporting standards and definitions for MRI/MRCP features.

More recently, both magnetic resonance cholangiopancreatography (MRCP) and ERCP have been primarily used to diagnose primary sclerosing cholangitis. MRCP is a noninvasive study that provides magnetic resonance images of the biliary tree.

Oct 18, 2019 · MR cholangiopancreatography and endoscopic retrograde cholangiopancreatography have high specificity and sensitivity for detection of primary disease and assessment of disease progression. However, many patients with PSC are still diagnosed incidentally at US or CT.

Magnetic resonance cholangiopancreatography (MRCP) is an alternative diagnostic test to ERCP and transhepatic cholangiogram for making the diagnosis of PSC. MRCP is a safe and non-invasive test that takes images of the bile pancreatic ductsand has replaced ERCP as the first imaging test in patients suspected of having PSC.

The diagnosis of PSC is made via a showing of elevated serum markers of cholestasis (AP, γGT) in combination with imaging findings – magnetic resonance cholangiopancreatography (MRCP) or endoscopic retrograde cholangiopancreatography (ERCP) demonstrating characteristic bile duct changes with multifocal strictures and segmental dilatations, when ...

Consider US or MRCP + serial CA 19-9 every 6-12 months to screen for cholangiocarcinoma (10-year cumulative risk 8%). If GB polyps >8 mm, recommend cholecystectomy to prevent GB adenocarcinoma, and recommend annual US for GB cancer surveillance.

Magnetic Resonance Cholangiopancreatography (MRCP) plays a crucial role in the treatment of PSC. MRCP provides detailed imaging of the bile ducts and liver, which helps healthcare providers assess disease severity, identify complications, and determine the most appropriate treatment approach.

Dec 14, 2021 · primary sclerosing cholangitis (PSC) is a rare, chronic, cholestatic liver disorder characterized by multifocal biliary strictures and progressive liver disease