Prostate-specific antigen (PSA) occurs in different molecular forms in serum: free PSA (fPSA) and complexed PSA (cPSA), the sum of which corresponds to total PSA (tPSA). In addition to tPSA, percent fPSA is widely used in the detection of prostate cancer.

Nov 1, 2010 · To determine the relationship between glomerular filtration rate (GFR) and free prostate-specific antigen (fPSA), percent-free PSA (%fPSA), and total PSA (tPSA) in patients with diminished kidney function not on dialysis, using nationally representative data.

Aug 12, 2014 · It is important for your doctor to check your prostate gland for enlargement or abnormalities, particularly as you age. In addition, there is now a blood test called the PSA, or prostate specific antigen test, which measures a substance that increases in the blood when prostate cancer has spread.

Sep 22, 2004 · BPH measures were divided between three obstruction measures (peak flow rates, postvoid residual, IPSS) and two prostatic enlargement measures (prostate volume, PSA). Elevated PSA in men without prostate cancer is a strong predictor of prostatic enlargement.

Jan 3, 2013 · Receiver operating characteristic (ROC) analysis was conducted to define the cutoff value of percent-free PSA among patients with impaired renal function. Correlations among percent-free PSA, age, GFR, BMI, and prostate size were analyzed in both the cancer and non-cancer cohorts, respectively.

Percent-free PSA has a negative relationship with GFR in the benign prostate group, while it does not in the prostate cancer group. Screening with current cutoff value of percent-free PSA can be applied to the patients with impaired renal function.

The incidence of %fPSA <25% was significantly lower in group A than in group B. GFR <60 ml/min/1.73 m(2) , fPSA and %fPSA <25% were significant predictors for the presence of prostate cancer in patients with tPSA between 4 and 10 ng/ml.

Jun 8, 2024 · Typically, patients with decreased renal function exhibit elevated levels of certain tumor markers. Prostate-specific antigen (PSA), a glycoprotein antigen produced by the prostate gland's epithelial cells and a member of the tissue kallikrein family, is among them.

To determine the relationship between glomerular filtration rate (GFR) and free prostate-specific antigen (fPSA), percent-free PSA (%fPSA), and total PSA (tPSA) in patients with diminished kidney function not on dialysis, using nationally representative data.

There was no association with a prostate volume >30 mL by an OR = 0.56 (95% CI 0.22–1.37) or PSA. = 1.17 (95% CI 0.47–2.81). Conclusion. There was a cross-sectional association between signs and symptoms of bladder outlet obstruction and …