Protein Phosphatase 2A, a Negative Regulator of the ERK …
PP2A is an important negative regulator of the extracellular signal-regulated kinase (ERK) signaling pathway and is involved in the control of many cellular functions including …
B56‐containing PP2A dephosphorylate ERK and their activity is ...
Feb 2, 2006 · The protein phosphatase 2A (PP2A) acts on several kinases in the extracellular signal‐regulated kinase (ERK) signaling pathway but whether a specific holoenzyme …
Activation of the ERK and JNK Signaling Pathways Caused by …
Inhibition of PP2A Activates the ERK Signaling Pathway. To determine in more detail whether hyperphosphorylation of tau in L199P brains is caused by up-regulated kinases, we analyzed …
Protein phosphatase 2A (PP2A) is a family of mamma-lian serine/threonine phosphatases that is involved in the control of many cellular functions including those mediated by extracellular …
Protein phosphatase 2A, a negative regulator of the ERK
Oct 1, 2004 · Protein phosphatase 2A (PP2A) is a family of mammalian serine/threonine phosphatases that is involved in the control of many cellular functions including those …
A new paradigm for regulation of protein phosphatase 2A
We propose dysregulation of SFK signaling in cancer and AD can lead to alterations in PP2A phosphorylation and subsequent deregulation of key PP2A substrates, including ERK and …
PP2A: more than a reset switch to activate pRB proteins during …
Treatment of RCS cells with FGF1 results in the autophosphorylation of FGFR3 and activated downstream targets such Phospholipase Cγ, AKT, ERK and p38 MAP kinases, but also …
Protein Phosphatase 2A, a Negative Regulator of the ERK …
Oct 1, 2004 · Protein phosphatase 2A (PP2A) is a family of mammalian serine/threonine phosphatases that is involved in the control of many cellular functions including those …
B56-containing PP2A dephosphorylate ERK and their activity …
The protein phosphatase 2A (PP2A) acts on several kinases in the extracellular signal-regulated kinase (ERK) signaling pathway but whether a specific holoenzyme dephosphorylates ERK …
Src kinase up-regulates the ERK cascade through inactivation of …
Jul 14, 2009 · Src induces up-regulation of ERK activity and its target transcription factors, CREB and ERα, through attenuation of PP2A activity. Therefore, activation of ERK is the result of a …