POU domain, class 3, transcription factor 4 is a protein that in humans is encoded by the POU3F4 gene found on the X chromosome. [ 5 ] [ 6 ] [ 7 ] POU3F4 is involved in the patterning of the …

Mar 30, 2025 · POU3F4 (POU Class 3 Homeobox 4) is a Protein Coding gene. Diseases associated with POU3F4 include Deafness, X-Linked 2 and Rare X-Linked Non-Syndromic …

Mutations involving the POU3F4 gene cause nonsyndromic hearing loss, which is a loss of hearing that is not associated with other signs and symptoms. Mutations in this gene cause a …

Mar 27, 2013 · HGNC Approved Gene Symbol: POU3F4. Cytogenetic location: Xq21.1 Genomic coordinates (GRCh38) : X:83,508,290-83,512,127 (from NCBI) The POU3F4 gene encodes a …

POU3F4 is a member of the POU-homedomain transcription factor family with a prominent role in inner ear development. Mutations in the human POU3F4 coding unit leads to X-linked …

Many X-linked non-syndromic hearing loss (HL) cases are caused by various mutations in the POU domain class 3 transcription factor 4 (POU3F4) gene. This study aimed to identify allelic …

POU3F4 mutations are associated with X-linked deafness; We concluded that the probable presence of the third window effect is not limited to the particular type of POU3F4 mutation. …

Apr 21, 2021 · Incomplete partition type III (IP-III) is a relatively rare inner ear malformation that has been associated with a POU3F4 gene mutation. The IP-III anomaly is mainly …

Jun 17, 2024 · Clinical resource with information about POU3F4, A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus., …

Sep 4, 2018 · We identified three causative mutations in POU3F4 for three probands and their extended families. In family 1468, we observed a novel deletion mutation, c.973delT, which is …