Apr 19, 2017 · Here, we show the expression of the Glycogen synthase kinase 3 (GSK3) MoGSK1 in M. oryzae is regulated by Mps1 MAP kinase, particularly under the stressed conditions.

The MPS1 MAPK is essential for conidiation, appressorial penetration, and plant infection in M. grisea . The mps1 deletion mutant is significantly reduced in aerial hyphal growth and conidiation, but it displays no obvious changes in the growth rate.

Mar 15, 2018 · The adapter protein Mst50 is involved in both Pmk1 and Mps1 pathways. Mip11 is a RACK protein that interacts with both Mst50 and Mck1. Pmk1 positively regulates Mst12, Mcm1, Sfl1, and likely other transcription factors during different infection processes.

Oct 1, 2023 · Moreover, we found that MoCdc25 was involved in regulating the transcription, translation and phosphorylation of Pmk1 and Mps1 (Fig. 6 A and B). Our results suggest that MoCdc25 may act upstream of Pmk1 and Mps1 MAPK signalling pathways in M. oryzae.

Sep 19, 2024 · With comparative phosphoproteomics analysis of samples at multiple time points, the authors characterized the full regulatory landscape of the Pmk1-mediated signaling pathway in detail, with novel targets of Pmk1 identified and functionally characterized.

Aug 18, 2021 · Thioredoxin Trx2 affects the activation of Mst7, which interacts with Pmk1 at the docking sites. Activated Pmk1 regulates the expression of genes important for appressorium formation, penetration, and invasive growth by Mst12, Mcm1, Sfl1, Tpc1, and possibly other transcription factors.

In the rice blast fungus Magnaporthe oryzae, the PMK1 MAP kinase, orthologous to yeast Fus3/Kss1, regulates late stages of appressorium formation and appressorial penetration, although cAMP...

In the rice blast fungus Magnaporthe oryzae, the Pmk1 and Mps1 MAP kinases with the TEY motif are essential for appressorium formation, penetration, and invasive growth. Osm1 is the third MAP kinase that has the TGY motif and functions in osmoregulation.

Nov 5, 2004 · The PMK1, MPS1, and OSM1 MAPK genes, which are homologous with yeast FUS3/KSS1, SLT2, and HOG1 (Gustin et al., 1998; Dohlman, 2002), respectively, have been shown to regulate appressorium formation, cell wall integrity, and osmoregulation in M. grisea.

Mar 23, 2018 · We showed that chemical genetic inhibition of a single fungal mitogen-activated protein (MAP) kinase, Pmk1, prevents M. oryzae from infecting adjacent plant cells, leaving the fungus trapped within a single plant cell.