In this review, we survey the impact of phosphorylation of various ion channels by PKC isoforms and examine the dependence of phosphorylated ion channels on phosphatidylinositol (4,5) …

In this review, we survey the impact of phosphorylation of various ion channels by PKC isoforms and examine the dependence of phosphorylated ion channels on phosphatidylinositol (4,5) …

Feb 26, 2025 · In this study, we show that calmodulin and protein kinase C-epsilon unmask PIP2 through the dissociation of myristoylated alanine-rich C-kinase substrate from membranes …

Jan 9, 2012 · Cycles of PIP2 synthesis and hydrolysis by PLC are thought to play a critical role in re-structuring the contractile ring throughout the duration of furrowing. PIP2-mediated …

Apr 30, 2021 · We show that PIP 2 controls both the PKC-mediated inhibition and the DAG- and lanthanide-mediated activation of TRPC5 currents via control of gating rather than channel cell …

Apr 26, 2016 · Our findings demonstrate that together Ca(2+)-PKC and the PIP2-binding peptide of MARCKS modulate the level of free PIP2, which serves as both a docking target and …

Jun 1, 2022 · In this review, we survey the impact of phosphorylation of various ion channels by PKC isoforms and examine the dependence of phosphorylated ion channels on …

Our results indicate that the depletion of membrane PIP 2 underlies receptor-mediated inhibition of IKs and that phosphorylation by PKC of the KCNE1 subunit underlies the GqPCR-mediated …

Sep 9, 2020 · Stimulation of TRPC1‐based SOCs requires protein kinase C (PKC) activity, with store‐operated PKC‐dependent phosphorylation of TRPC1 essential for channel opening by …

Here, we show that Ca 2+ /calmodulin (CaM) and protein kinase C (PKC)–epsilon rescue vesicle fusion from the arrest by dissociating the effector domain (ED) of MARCKS from membranes …