Dual Regulation of Glycogen Synthase Kinase 3 …
The ability of PKC to phosphorylate GSK3α/β was further confirmed in experiments using the PKC activator phorbol 12-myristate-13-acetate (PMA). PMA robustly stimulated pleckstrin and GSK3α/β phosphorylation in a PKC …
Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases
Nov 27, 2021 · Glycogen synthase kinase-3 (GSK3) may be the busiest kinase in most cells, with over 100 known substrates to deal with. How does GSK3 maintain control to selectively …
PKCα-GSK3β-NF-κB signaling pathway and the possible ... - PubMed
In this study, we show that GSK3β antagonized TRAIL-induced apoptosis in H1299 NSCLC cells, and determined that the PKCα isozyme is an upstream regulator of GSK3β that …
- Author: Xuejuan Gao, Fengmei Xu, Huan-Tian Zhang, Miaojuan Chen, Wensi Huang, Qihao Zhang, Qingzhong Zeng, L...
- Publish Year: 2016
- Studies of PKC GSK3B
Cdc42 regulates GSK-3β and adenomatous polyposis coli to
Jan 29, 2003 · Cdc42-dependent phosphorylation of GSK-3β occurs specifically at the leading edge of migrating cells, and induces the interaction of adenomatous polyposis coli (Apc) …
- Author: Sandrine Etienne-Manneville, Alan Hall
- Publish Year: 2003
Activated PKB/GSK-3β synergizes with PKC-δ signaling in …
Jan 1, 2021 · By demonstrating independent modulation of PKC- δ and PKB/GSK-3 β /Fyn signaling, we highlight the ability of DT to exploit both nuclear import and export regulation of …
- Author: Hao Zeng, Lingling Wang, Jiawei Zhang, Ting Pan, Yinghua Yu, Jingxia Lu, Ping Zhou, Hua Yang, Ping L...
- Publish Year: 2021
GSK3β: A Master Player in Depressive Disorder Pathogenesis and ...
Glycogen synthase kinase 3β (GSK3β), originally described as a negative regulator of glycogen synthesis, is a molecular hub linking numerous signaling pathways in a cell. Specific GSK3β …
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Glycogen synthase kinase-3 beta - Wikipedia
Glycogen synthase kinase-3 beta, (GSK-3 beta), is an enzyme that in humans is encoded by the GSK3B gene. [5] [6] In mice, the enzyme is encoded by the Gsk3b gene. [7] Abnormal …
Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by
Glycogen synthase kinase-3 beta, (GSK-3 beta), is an enzyme that in humans is encoded by the GSK3B gene. In mice, the enzyme is encoded by the Gsk3b gene. Abnormal regulation and expression of GSK-3 beta is associated with an increased susceptibility towards bipolar disorder.
Wikipedia · Text under CC-BY-SA licenseExpression and regulation of glycogen synthase kinase 3 in human ...
In the present study, we examined GSK-3 expression and regulation in human neutrophils. GSK-3α was found to be the predominant isoform, it was constitutively expressed and cell …
Dual Regulation of Glycogen Synthase Kinase 3 …
The ability of PKC to phosphorylate GSK3α/β was further confirmed in experiments using the PKC activator phorbol 12-myristate-13-acetate (PMA). PMA robustly stimulated pleckstrin and GSK3α/β phosphorylation in a PKC …
