Pharmacokinetics is the study of how an organism affects the drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, …

Assays used in preclinical development to support PK/PD analysis typically include drug or surrogate molecule assays, target engagement or biomarker assays, and ADA assays.

To support PK studies at all phases of development, we offer assay development, validation, and implementation using ELISA and Meso Scale Discovery (MSD) assays for biologics, and flow …

Ligand-binding assays (LBA) are widely used for the analysis of protein biotherapeutics and target ligands (L) to support pharmacokinetics/pharmacodynamics (PK/PD) and safety assessments.

Use of a single PK assay for quantification of multiple products requires a scientifically sound testing strategy to evaluate bioanalytical comparability of the test products within the method, …

To ensure the safety and efficacy of these molecules, robust bioanalytical pharmacokinetic (PK) assays that can reliably quantify drug concentrations are required. This data are used to …

PK evaluations help to define the proper dosage, route, and schedule of administration during preclinical and clinical studies. BioAgilytix provides PK assay development, validation, and …

Meet CellCarta's PK assays for biologics. Discover how our tailored assays offer accuracy and efficiency in pharmacokinetic analysis.

The most optimal approach is to develop a single PK assay, using a single analytical standard, for quantitative measurement of the biosimilar and reference products in serum matrix.

May 19, 2022 · Assessing the PK, PD and immunogenicity allows drug development sponsors and their CRO partners to build a bigger picture and deliver insights for more informed …