PIAS1 - Wikipedia
It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in …
PIAS1 Gene - GeneCards | PIAS1 Protein | PIAS1 Antibody
Mar 30, 2025 · PIAS1 (Protein Inhibitor Of Activated STAT 1) is a Protein Coding gene. Diseases associated with PIAS1 include Nephronophthisis and Germ Cell Cancer. Among its related …
PIAS1 protein inhibitor of activated STAT 1 [ Homo sapiens …
Mar 8, 2025 · Title: Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation. SUMOylation and coupling of eNOS mediated by PIAS1 contribute to …
Protein Inhibitor of Activated STAT 1 (PIAS1) Is Identified as the …
PIAS1 was found to interact with C/EBPβ through the SAP (scaffold attachment factor A/B/acinus/PIAS) domain and SUMOylate it, leading to increased ubiquitination and …
Quantitative SUMO proteomics identifies PIAS1 substrates
Feb 11, 2020 · Here we used quantitative SUMO proteomics to identify potential substrates of PIAS1 in a system-wide manner. We identified 983 SUMO sites on 544 proteins, of which 62 …
Regulation of gene-activation pathways by PIAS proteins in the
Aug 1, 2005 · PIAS1 has specific effects on cytokine-mediated signalling by selectively regulating a subset of interferon- or tumour-necrosis-factor-responsive genes. PIAS1 is important in …
PIAS1 selectively inhibits interferon-inducible genes and is
Aug 15, 2004 · Using PIAS1-deficient cells, we show that PIAS1 selectively regulates a subset of IFN-γ- or IFN-β-inducible genes by interfering with the recruitment of STAT1 to the gene …
PIAS family in cancer: from basic mechanisms to clinical applications
PIAS1 promotes tumorigenesis via SUMOylation and proteosomal degradation of PML. Also shown is the antagonistic role of PIAS1 in APL remission by recruiting RNF4-mediated …
PIAS1 - an overview | ScienceDirect Topics
PIAS1 is a genuine chromatin-bound AR coregulator and is upregulated in PCa. It has been proved that PIAS1 mediating modification with SUMO3 masks different genomic loci from AR …
Protein inhibitor of activated STAT 1 (PIAS1) is identified as ... - PubMed
PIAS1 was found to interact with C/EBPβ through the SAP (scaffold attachment factor A/B/acinus/PIAS) domain and SUMOylate it, leading to increased ubiquitination and …