Platelet factor 4 - Wikipedia
Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . This chemokine is released from alpha …
Platelet factor 4(PF4) and its multiple roles in diseases
Mar 1, 2024 · Platelet factor 4 (PF4) combines with heparin to form an antigen that could produce IgG antibodies and participate in heparin-induced thrombocytopenia (HIT). PF4 has attracted …
Antibodies against Platelet Factor 4 and Their Associated …
Antibodies against platelet factor 4 (PF4), a protein released from alpha-granules of activated platelets, may cause a number of pathophysiological conditions. The most commonly known is …
What for platelet factor 4? | Blood - American Society of …
Aug 15, 2007 · PF4, a member of the CXC family of chemokines, is the most abundant protein in platelet α-granules and is released into the local environment following platelet activation. …
PF4 - Immucor
PF4 Enhanced and PF4 IgG have been designed to detect antibodies implicated in causing Heparin Induced Thrombocytopenia (HIT). LIFECODES PF4 is offered in multiple kit formats …
Platelet factor 4 (PF4) and its multiple roles in diseases - PubMed
Herein, we discussed the characteristics and biological functions of PF4, summarized PF4-mediated signaling pathways, and discussed its multiple roles in diseases to inform novel …
Emphasis on the Role of PF4 in the Incidence, Pathophysiology …
Platelet factor 4 (PF4), also known as chemokine CXCL4, is a cationic, 7.8 kDa protein which forms tetramers at physiological pH and ionic strength [24-26]. PF4 is released from the alpha …
PF4 Gene - GeneCards | PLF4 Protein | PLF4 Antibody
Mar 30, 2025 · PF4 (Platelet Factor 4) is a Protein Coding gene. Diseases associated with PF4 include Erythromelalgia and Essential Thrombocythemia. Among its related pathways are MIF …
PF4 platelet factor 4 [Homo sapiens (human)] - Gene - NCBI
Feb 8, 2025 · Platelet factor 4-positive thrombi adhering to the ventricles of a ventricular assist device in patients with heparin-induced thrombocytopenia type II. Beiras-Fernandez A, et al. …
Gene Pf4: Platelet Factor 4 - Function, Research, & Clinical …
Explore the role of Gene Pf4 (Platelet Factor 4) in thrombosis, inflammation, and cancer research. Learn about its function, clinical significance, and potential therapeutic applications.