Jan 1, 2025 · What is drusenoid PED OCT? Drusenoid PED OCT refers to the presence of drusen-like deposits in the subretinal space as visualized by optical coherence tomography (OCT). These deposits are associated with age-related macular degeneration (AMD) and …

OCT: OCT demonstrates (Figure 1C, arrow) irregular RPE elevation in contrast to the smooth elevation of a serous PED, with heterogenous features often along the back surface of the detached RPE. Scant overlying subretinal fluid may sometimes be seen.

Feb 15, 2021 · PEDs can be serous (which will look dark/optically empty), drusenoid (moderately reflective but generally uniform), fibrovascular (hyperreflective and heterogeneous) or hemorrhagic (where the anterior aspect is hyperreflective but the blood causes posteror shadowing, as seen in Figure 9). 5.

Jan 1, 2025 · Drusenoid PED is typically diagnosed through a comprehensive eye examination, including optical coherence tomography (OCT) and fundus photography to visualize the retinal layers and identify any pigment epithelial detachments.

In AMD, three main types of PED are observed: serous, drusenoid and fibrovascular/haemorrhagic. The pathogenesis of serous PEDs in AMD is related to a spectrum of different mechanisms ranging from degenerative changes in Bruch’s membrane to the formation of …

This is an OCT of a pigment epithelial detachment (PED) in wet AMD with some adjacent subretinal fluid (SRF) and an overlying area of focal intraretinal fluid (IRF). Drusen: Lumps of deposits under the RPE.

Jun 15, 2022 · OCT-A confirms avascularity of a drusenoid pigment epithelial detachment (PED): (A) Color photo shows soft coalesced drusen with overlying hyperpigmentary changes. (B) Structural OCT reveals a PED with medium uniform internal reflectivity, no fluid and shadowing artifacts from the overlying intraretinal pigmentary migration.

Mar 20, 2025 · Swept-source OCT improves visualization of deeper retinal layers, enhancing PED boundary delineation and Bruch’s membrane assessment. Automated segmentation algorithms allow for PED volume quantification, helping track progression and assess risk.

Clinically, PEDs appear as domed elevations of the RPE layer and may be associated with other signs of AMD, including drusen, overlying RPE hyperpigmentation, subretinal fluid, or subretinal hemorrhage. On OCT imaging, a PED is identified when a space is formed between the RPE and Bruch’s membrane.

Sep 15, 2012 · As noted, OCT can differentiate drusen from exudates in 100% of the cases. (See www.retinarevealed.com case study archive #44 for many more images, differential diagnoses and discussion of the various etiologies of white dots and spots.)