5 days ago · Western blot analysis of extracts from SW-13, NIH/3T3, Jurkat and PC12 cells, using PDK1 Antibody. Cat. Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml …

Feb 7, 2011 · PDK1 has 2 isoforms with the MW of 49 and 52 kD, and a 28aa-transit-peptide in the N-terminal can be removed in the mature form. This antibody is specific to PDK1. …

Jun 6, 2023 · Monomeric full-length PDK1 1-556 had D max = 110 Å and Rg = 34.8 Å, with the MW estimated between 67 and 79 kDa by different calculation approaches (Table 1).

Pyruvate dehydrogenase kinase (also pyruvate dehydrogenase complex kinase, PDC kinase, or PDK; EC 2.7.11.2) is a kinase enzyme which acts to inactivate the enzyme pyruvate …

We provide genetic evidence that PDK1 is essential for mouse embryonic development, and regulates cell size independently of cell number or proliferation, as well as insulin’s ability to …

Phospho-PDK1 (Ser241) (C49H2) Rabbit mAb detects PDK1 only when phosphorylated at Ser241. Monoclonal antibody is produced by immunizing animals with a synthetic …

3-Phosphoinositide-dependent kinase 1 (PDK1), also known as PKB kinase, was identified as the activator of the survival kinase Akt/PKB. Several important substrates of PDK1 include p70S6 …

Feb 5, 2013 · Phosphoinositide-dependent kinase 1 (PDK1) plays an important role in integrating the T cell antigen receptor (TCR) and CD28 signals to achieve efficient NF-κB activation. …

Dec 12, 2021 · PDK1 also phosphorylates PKCα and other isoforms in a reaction essential to their stability, maturation, and kinase activity . In this study, we quantify the affinity of PDK1-PKC …

Polyclonal Antibody for studying PDK1 (Ser241) phosphate. Validated for IP, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-PDK1 (Ser241) Antibody …