The Bell P-63 Kingcobra is an American fighter aircraft that was developed by Bell Aircraft during World War II. Based on the preceding Bell P-39 Airacobra, the P-63's design incorporated suggestions from P-39 pilots and was superior to its predecessor in virtually all respects.

Tumor protein p63, typically referred to as p63, also known as transformation-related protein 63, is a protein that in humans is encoded by the TP63 (also known as the p63) gene. [5] [6] [7] [8]

4 days ago · Immunohistochemistry demonstrated a strong nuclear expression of p63 in the basal cells of the hyperplastic glands. These features correlate with benign prostatic hyperplasia. Which of the statements below regarding p63 is true? B. Loss of p63 expression correlates with poor prognosis in urothelial carcinoma.

Nov 14, 2023 · p63 is a protein made by both normal cells and tumour cells. Pathologists use a test called immunohistochemistry to see p63 inside cells.

Jan 25, 2021 · Tumor protein 63 (p63) is a transcription factor of the p53 gene family involved in differentiation of several tissues including squamous epithelium. p63 immunohistochemistry is broadly used for tumor classification but published data on its expression in cancer is conflicting.

p63 (also known as TP63) is a transcription factor of the p53 family, along with p73. Multiple isoforms of p63 have been discovered and these have diverse functions encompassing a wide array of cell biology. p63 isoforms are implicated in lineage ...

The p63 protein is a master regulatory transcription factor that plays crucial roles in cell differentiation, adult tissue homeostasis, and chromatin remodeling, and its dysregulation is associated with genetic disorders, physiological and premature aging, and cancer.

Dec 26, 2023 · "P63" is a term used in medical testing, specifically in pathology, which is the study of disease. It refers to a protein that is often looked for in cells when doctors are trying to identify certain types of diseases.

Sep 11, 2020 · Multiple isoforms of p63 have been discovered and these have diverse functions encompassing a wide array of cell biology. p63 isoforms are implicated in lineage specification, proliferative potential, differentiation, cell death and survival, DNA …

Jul 18, 2024 · p63 is a commonly used immunostain. p63, like most other "p" stains, is a nuclear stain. Nuclear staining. Stains basal cells in a normal squamous epithelium. Superficial cells are typically negative. In dysplasia, the staining is seen more superficially, [1] as one might expect as most squamous carcinomas are positive for p63. Note: