The P300 (P3) wave is an event-related potential (ERP) component elicited in the process of decision making. It is considered to be an endogenous potential, as its occurrence links not to the physical attributes of a stimulus, but to a person's reaction to it.

The P300 wave is a positive deflection in the human event-related potential. It is most commonly elicited in an "oddball" paradigm when a subject detects an occasional "target" stimulus in a regular train of standard stimuli.

Oct 29, 2020 · What is P300 event-related potential? The P300 wave is an event-related brain potential measured using electroencephalography (EEG). P300 refers to a spike in activity approximately 300ms following presentation of the target stimulus, which is alternated with standard stimuli to create an ‘oddball’ paradigm, which is most commonly auditory.

The P300 is a positive wave occurring approximately in 300 milliseconds following stimulus presentation [24, 25]. In contrast to some earlier components within the ERP, the P300 has been argued to reflect higher-level processes that are sensitive to task context, such as attentive selection [24, 26].

The P300 continues to be an important signature of cognitive processes such as attention and working memory and of its dysfunction in neurologic and mental disorders. It is increasingly being investigated as a potential genetic marker of mental disorders.

The P300 component, or cognitive potential, is a positive potential elicited by the recognition of a rare stimulus (oddball paradigm) within a series of frequent stimuli and corresponds to the largest positive wave after the N1-P2 complex.

Feb 28, 2017 · According to Schochat, 5 P300 is identified as a wave of positive polarity with latency of ∼300 milliseconds post-stimulus, obtained after subtracting the trace corresponding to nonstandard stimuli from the trace corresponding to standard stimuli.

The P300 continues to be an important signature of cognitive processes such as attention and working memory and of its dysfunction in neurologic and mental disorders. It is increasingly being investigated as a potential genetic marker of mental disorders.

Jan 24, 2025 · This blog describes what the P300 is and how you can detect it. It includes a practical example of how a P300 response was measured using TMSi's SAGA, including the experimental protocol, a sample dataset, and all acquisition and processing codes.

The P300 wave, as a cognitive event-related po-tential, allows for the analysis of decision-making processes in the brain cortex, which is significant in neurodegenerative dis-eases. The research results conducted by the author confirm that studying the P300 wave can be useful in …