P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene. [5] [6] The product of this gene, P2Y 2 belongs to the family of G-protein coupled receptors. This family has …

Mar 30, 2025 · P2RY2 (Purinergic Receptor P2Y2) is a Protein Coding gene. Diseases associated with P2RY2 include Dry Eye Syndrome and Cystic Fibrosis. Among its related pathways are …

Feb 15, 2019 · We aimed to determine whether blocking extracellular ATP-P2RY2 axis could be a potential therapeutic approach for PDAC treatment. Experimental design: Expression of …

Jan 1, 2022 · P2Y purinoceptor 2 (P2RY2) is involved in the regulation of cell proliferation and apoptosis. The aim of this study was to explore the effects of P2RY2 on cerebral …

Jun 6, 2022 · We discover that selinexor activates PI3Kγ-dependent AKT signaling in AML by upregulating the purinergic receptor P2RY2. Inhibiting this axis potentiates the anti-leukemic …

P2RY2 is a prognostic marker in Pancreatic adenocarcinoma, Rectum adenocarcinoma

Jan 4, 2025 · Title: AKT/GSK-3beta/VEGF signaling is involved in P2RY2 activation-induced the proliferation and metastasis of gastric cancer. P2Y2R-mediated transactivation of VEGFR2 …

Results show that purinergic receptor P2Y2 (P2Y2R) requires N-glycosylation for expression on the cell surface. Data indicate that knockdown of caveolin-1 (Cav-1) expression causes …

The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled …

Aug 27, 2009 · P2RY2 has an important function in the regulation of blood pressure by activating adenosine triphosphate (ATP). The aim of this study was to investigate the association …