MAGT1 is required for HeLa cell proliferation through regulating p21 …
We showed that cell proliferation was substantially restricted by S-phase arrest and apoptosis in the MAGT1-knocked down cells, which was further confirmed by the increased expression of …
The cGAS/STING/TBK1/IRF3 innate immunity pathway maintains
Apr 13, 2020 · Here, we demonstrate for the first time that stably decreasing cGAS expression levels in different cancer cell lines (HeLa and U2OS) facing nocodazole-induced mitotic arrest …
Regulation of p21/CIP1/WAF-1 mediated cell-cycle arrest by …
We found a significant loss of p21 mRNA expression in RNASEL−/− MEFs and that the overexpression of RNase L in HeLa cells induces p21 mRNA expression. The p21 mRNA half …
TFEB Modulates p21/WAF1/CIP1 during the DNA Damage Response
Pharmacological inhibition of p21, instead, abrogates TFEB-mediated protection during the DNA damage response. Together, our findings uncover a novel and direct role of TFEB in the …
Induction of p53, p21 and apoptosis by silencing the NF90/NF45 …
Dec 3, 2012 · In HeLa cells, p21 messenger-RNA (mRNA) increased concomitantly but the level of p53 mRNA was unaffected. RNA interference directed against p53 prevented the induction …
INMAP Overexpression Inhibits Cell Proliferation, Induces …
Jan 30, 2015 · INMAP combines with NuMA to form a complex, and it might assist NuMA to recruit CDK8 to the promoter region of the p21 gene in cell-cycle arrest. In addition, INMAP …
Targeting the TGF-β-p21 axis: a critical regulator of ... - Springer
Feb 28, 2025 · We confirmed the cytotoxicity, anti proliferative effect of bleomycin in HeLa cells. Meanwhile, bleomycin also led to the suppression of cell migration, invasion. Relative gene …
Regulation of p21 expression for anti-apoptotic activity of DDX3 ...
The relationship between DDX3 and the inhibition of p21 and apoptosis was investigated. Results: Sanguinarine was determined to be the most effective intrinsic apoptosis-inducing agent in …
Regulation of p21/CIP1/WAF-1 mediated cell-cycle arrest by ... - PubMed
We found a significant loss of p21 mRNA expression in RNASEL(-/-) MEFs and that the overexpression of RNase L in HeLa cells induces p21 mRNA expression. The p21 mRNA half …
MAGT1 is required for HeLa cell proliferation through regulating p21 ...
Apr 8, 2021 · We showed that cell proliferation was substantially restricted by S-phase arrest and apoptosis in the MAGT1-knocked down cells, which was further confirmed by the increased …
- Some results have been removed