— In the first 60 days of the Trump Administration, the U.S. Office of Personnel Management (OPM) has led a sweeping transformation of the federal workforce.

The U.S. Office of Personnel Management (OPM) serves as the chief human resources agency and personnel policy manager for the Federal Government. Explore how OPM uses – and plans to use – the resources appropriated by Congress to achieve its mission.

OPM is here to help you transition from serving the American people to enjoying your retirement. These links are useful to new and existing retirees throughout their retirement journey. Retiring …

The crystal structure of the major outer membrane protein U (OmpU) from Vibrio cholerae has been determined, which exhibits distinct structural features from other structurally characterized porins and provides the structural basis for the bacterial invasion and phage recognition.

Jan 1, 2022 · OmpU, the most abundant and conserved outer membrane protein among Vibrio species, induces proinflammatory response and apoptosis in host cells. OmpU activates receptor-mediated pathways in several target cells and enters the cell via clathrin dependent endocytosis.

OmpU is a multimeric, cation selective outer membrane protein of Vibrio and related species that non-covalently interact with peptidoglycan layer. Interaction of OmpU with human host cells triggers signaling pathways to promote cytokine secretion, reactive oxygen species production, and caspase independent death in immune and epithelial cells.

Outer membrane proteins (OMPs) do not fold as they emerge from the ribosome. Rather, unfolded polypeptide chains of OMPs are transported through the translocon in an extended form.

Outer membrane protein U (OmpU) is a major porin from Vibrio alginolyticus and has been considered a vaccine candidate against infection by V. alginolyticus.

Mar 5, 2015 · Outer membrane protein U (OmpU) is a conserved major outer membrane protein, which is widely present in pathogenic vibrio, such as Vibrio cholerae, Vibrio alginolyticus and Vibrio vulnificus. OmpU protein was shown to be an important adhesin in Vibrio cholerae and Vibrio vulnificus [7 – 10].

We show that the major OMP, OmpU, affects biofilm formation. We systematically analyze the impact of OmpU on the production and localization of key matrix components and reveal that it predominantly impacts VPS production.