The NPAS4 gene is a neuronal activity-dependent immediate early gene that has been identified as a transcription factor. The protein regulates the transcription of genes that control inhibitory …

Mar 30, 2025 · NPAS4 (Neuronal PAS Domain Protein 4) is a Protein Coding gene. Diseases associated with NPAS4 include Autism Spectrum Disorder and Inflammatory Bowel Disease …

Activated Npas4 regulates the transcription of multiple genes, such as other transcription factors, channel proteins, G-protein signaling molecules, kinases, phosphatases, and genes involved …

Npas4 is an activity dependent transcription factor which is responsible for gearing the expression of target genes involved in neuro-transmission. Despite the importance of Npas4 in many …

Nov 6, 2013 · The transcription factor NPAS4 enables neurons to distinguish synaptic inputs received at their soma or dendrites; sensory stimulation increases NPAS4 which promotes …

May 22, 2014 · Npas4 is an early-response transcription factor that is enriched in the brain and induced in excitatory neurons specifically upon calcium influx and that has been suggested to …

Mar 14, 2016 · Npas4 is involved in activity-dependent synaptic modulation in both excitatory and inhibitory neurons. It regulates the expression of a large number of activity-regulated genes …

Dec 1, 2020 · Neuronal PAS domain protein 4 (Npas4) is a recently discovered calcium-dependent transcription factor that regulates the activation of genes involved in the …

Npas4 is a transcription factor, which is highly expressed in the brain and regulates the formation and maintenance of inhibitory synapses in response to excitatory synaptic activity.

Dec 1, 2020 · Activated Npas4 regulates the transcription of multiple genes, such as other transcription factors, channel proteins, G-protein signaling molecules, kinases, phosphatases, …