- PMAIP1 genePhorbol-12-myristate-13-acetate-induced protein 1 is a protein that in humans is encoded by the PMAIP1 gene, and is also known as Noxa. [3][4][5] Noxa (Latin for damage) is a pro- apoptotic member of the Bcl-2 protein family. [6]en.wikipedia.org/wiki/Phorbol-12-myristate-13-acetate-induced_protein_1
NOXA1 Gene - GeneCards | NOXA1 Protein | NOXA1 Antibody
Mar 30, 2025 · This gene encodes a protein which activates NADPH oxidases, enzymes which catalyze a reaction generating reactive oxygen species. The encoded protein contains four N-terminal tetratricopeptide domains and a C-terminal Src homology 3 domain.
See results only from genecards.orgPmaip1
PMAIP1 (Phorbol-12-Myristate-13-Acetate-Induced Protein 1) is a Protein Coding gene. Diseases associated with PMAIP1 include Leukemia and …
Phorbol-12-myristate-13-acetate-induced protein 1 - Wikipedia
Phorbol-12-myristate-13-acetate-induced protein 1 is a protein that in humans is encoded by the PMAIP1 gene, and is also known as Noxa.
Noxa (Latin for damage) is a pro-apoptotic member of the Bcl-2 protein family. Bcl-2 family members can form hetero- or homodimers, and they act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities…Wikipedia · Text under CC-BY-SA license- Estimated Reading Time: 4 mins
Noxa: at the tip of the balance between life and death
Initial observations indicated that Noxa is a primary p53-response gene. Noxa mRNA is rapidly induced after adenovirus-mediated introduction of p53 into MEF derived from p53−/− or wt mice and in wt thymocytes subjected to γ-irradiation …
PMAIP1 Gene - GeneCards | APR Protein | APR Antibody
Mar 30, 2025 · PMAIP1 (Phorbol-12-Myristate-13-Acetate-Induced Protein 1) is a Protein Coding gene. Diseases associated with PMAIP1 include Leukemia and Mantle Cell Lymphoma. Among its related pathways are Intrinsic Pathway for …
NOXA the BCL-2 Family Member behind the Scenes in Cancer …
Jul 7, 2020 · NOXA is a critical mediator of stress responses to anticancer drugs. This BH3-only protein sets the apoptotic threshold in cancer cells in response to chemotherapies by …
- Author: Alison Dumont, Steven Lohard, Laurent Maillet, Philippe P Juin, Sophie Barillé-Nion
- Publish Year: 2020
NOXA1 - Wikipedia
NADPH oxidase activator 1 is an enzyme that in humans is encoded by the NOXA1 gene. [5] [6]
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Integral role of Noxa in p53-mediated apoptotic response - PMC
We studied the role of Noxa, one of the transcriptional targets of p53 that encodes a proapoptotic protein of the Bcl-2 family, by the gene-targeting approach.
58801 - Gene ResultPmaip1 phorbol-12-myristate-13-acetate …
Feb 8, 2025 · Bmi1 controls memory CD4(+) Th1/Th2 cell survival and functions through the direct repression of the Noxa gene. Results indicate that, at least in fibroblasts and …
BH3-only Protein Noxa Is a Mediator of Hypoxic Cell Death …
Here we have demonstrated that Noxa, a member of BH3-only Bcl-2 family proteins, is an HIF-1α–dependent hypoxia-inducible gene and mediates hypoxic cell death in an ROS-dependent …
NOXA1 Gene: Role in Apoptosis, Cancer, and Therapeutic Potential
Explore the role of the NOXA1 gene in apoptosis, cancer development, and its potential as a therapeutic target. Learn about its regulation, function, and research advancements.
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