Aug 29, 2014 · The triad is a key muscle substructure responsible for controlling muscle contraction. Abnormalities in the triad are an emerging primary cause of an eclectic array of distinct skeletal myopathies called triadopathies.

Mar 6, 2023 · Neuromuscular junction (NMJ) is responsible for the chemical transmission of the electrical impulse from a nerve to the muscle ( skeletal/ smooth/ cardiac) in order to produce an appropriate muscle contraction.

May 1, 2023 · For convenience and understanding, the structure of NMJ can be divided into three main parts: a presynaptic part (nerve terminal), the postsynaptic part (motor endplate), and an area between the nerve terminal and motor endplate (synaptic cleft).

In the histology of skeletal muscle, a triad is the structure formed by a T tubule with a sarcoplasmic reticulum (SR) known as the terminal cisterna on either side. [1] Each skeletal muscle fiber has many thousands of triads, visible in …

The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating in the motor neuron to action potentials in the muscle fiber. The ...

... triad is an essential skeletal muscle substructure. It represents the close apposition of the transverse tubule (T- tubule) membrane with 2 flanking terminal cisternae of the sarcoplasmic...

Here, we describe a novel heterologous co-culture in vitro method using rat spinal cord explants with dorsal root ganglia and murine primary myoblasts to study neuromuscular junctions.

Dec 1, 2016 · We used NMJ-morph to generate baseline morphological reference data for 21 separate pre- and post-synaptic variables from 2160 individual NMJs belonging to nine anatomically distinct populations of synapses, revealing systematic differences in NMJ morphology between defined synaptic populations.

The specialized site of the skeletal muscle where a motor neuron’s axon terminal meets the muscle fiber is called the neuromuscular junction (NMJ) (Figure \(\PageIndex{2}\)). This is where the muscle fiber first responds to signaling by the motor neuron.

Which of the choices below correctly describes how an action potential generated at the neuromuscular junction (NMJ) is converted to excitation in the muscle fiber? An action potential in the motor neuron causes ACh to be released into the synaptic cleft.