This animated phonics song helps children learn the sound of the ending blend NK in English. A blend is a combination of letters where each letter makes its...

Cell type: Natural killer cell; CL= CL_0000623. Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia. Malignant hematopoietic cell lines: in vitro …

NKL cells are strictly dependent on interleukin-2 (IL-2) for sustained growth and die if deprived of IL-2 for more than 7 days. NKL cells proliferate in response to concentrations of IL-2 as low as 1 pM, but an optimal proliferative response requires approximately 100 pM IL-2.

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NKL (Upper) or pNK (Lower Left) cells, pretreated for 30 min at 37°C with either DMSO, 20 μM p38 MAPK inhibitor SB, 10 μM MEK1/2 inhibitor PD, 10 μM JNK inhibitor SP600125 (SP), or potent peptide inhibitor D-JNK-1 were tested for lysis of 51 Cr-labeled K562 cells.

Nov 4, 2008 · We established two Epstein–Barr virus (EBV)-infected NKL sublines, which acquired stress resistant phenotype against DNA damage and starvation compared with EBV-negative NKL.

Genetic modification of natural killer (NK) cells is a potential approach to gene-based immunotherapy of cancer. We created human interleukin-15 (hIL-15) gene-modified NKL cells and investigated their functional characterization in vitro.

Jul 31, 2018 · Our results demonstrated that this recombinant protein specifically lyses leukemia cells by NK cells, which may lead to development of a novel strategy for treating leukemia and other tumors. NK cells are cytotoxic lymphocytes that play a …

Jan 1, 2004 · The NKL cell line was established from the peripheral blood of a patient with CD3 −, CD16 + CD56 + large granulocyte leukemia. The morphology of these cells resembles that of normal activated NK cells with very similar proliferative responses, natural killing and antibody-dependent cellular cytotoxicity (ADCC) (Robertson et al., 1996).

Jun 21, 2013 · Here we describe the in vitro growth transformation of functional human NK cells by Herpesvirus saimiri (HVS), a primate rhadinovirus. NK cells are non-B, non-T lymphocytes that account for...