Urinary neutrophil gelatinase-associated lipocalin (NGAL) has shown promise in differentiating acute tubular necrosis (ATN) from other types of acute kidney injuries (AKIs) in cirrhosis, particularly hepatorenal syndrome (HRS).

Since serum creatinine is known to be an inadequate and late marker of AKI, NGAL might soon emerge as a troponin-like early marker for AKI. Recent evidence also suggests its role as a biomarker in a variety of other renal and non-renal conditions.

Neutrophil gelatinase-associated lipocalin (NGAL), also called lipocalin-2, is a small secretory glycoprotein that is found in neutrophils. It is also expressed at very low concentrations in a wide range of human tissues including kidney, lungs, stomach, and liver.

Neutrophil gelatinase-associated lipocalin (NGAL) is an emerging biomarker for the early detection of AKI. Studies have shown NGAL to be a highly induced protein in the kidney after ischemic or nephrotoxic injury.

Neutrophil gelatinase‐associated lipocalin (NGAL) is a new useful biomarker for the early diagnosis of acute kidney injury. The aim of the study was to compare two analytical methods for measurement of urinary NGAL: enzyme‐linked immunosorbent assay ...

May 11, 2021 · NGAL was assessed for its ability to discriminate ATN from non-ATN AKI and to predict 90-day outcomes. Results: Among patients with AKI, 57 (35%) had prerenal AKI, 55 (34%) had HRS, and 49 (30%) had ATN, with a median serum creatinine of 2.0 (interquartile range 1.5, 3.0) mg/dL at enrollment.

Urine neutrophil gelatinase-associated lipocalin (NGAL) is a diagnostic test that plays a crucial role in identifying and managing kidney health issues. This test measures the levels of NGAL protein in urine, serving as an early biomarker for kidney …

Background: Neutrophil gelatinase-associated lipocalin (NGAL), an iron-transporting protein rapidly accumulating in the kidney tubules and urine after nephrotoxic and ischemic insults, has been put forward as an early, sensitive, non-invasive biomarker for acute kidney injury (AKI).

Neutrophil gelatinase-associated lipocalin (NGAL) is a 25-kDa protein that is secreted mostly by immune cells such as neutrophils, macrophages, and dendritic cells. Its production is stimulated in response to inflammation. The concentrations of NGAL can be measured in plasma, urine, and biological fluids such as peritoneal effluent.

Apr 25, 2019 · Neutrophil gelatinase-associated lipocalin (NGAL) is an emerging biomarker for earlier identification of acute kidney injury (AKI). Using similar methodology, a reference interval for urine NGAL in adults was determined to be ≤113 ng/mL.