Expression of the transcription factor NFAT2 in human neutrophils: IgE ...
Jul 15, 2007 · Our results provide evidence that NFAT2 is constitutively expressed in human neutrophils, and after IgE-dependent activation operates as a transcription factor in the …
Monomeric IgE Stimulates NFAT Translocation Into the Nucleus, a …
Apr 1, 2004 · In this paper we report that monomeric IgE (SPE-7 IgE and H1 DNP-ε-206 IgE) stimulates rat basophilic leukemia (RBL)-2H3 mast cells to raise cytosol Ca 2+, PLC and PLD …
Expression of the transcription factor NFAT2 in human neutrophils: IgE …
Jul 15, 2007 · Our results provide evidence that NFAT2 is constitutively expressed in human neutrophils, and after IgE-dependent activation operates as a transcription factor in the …
Monomeric IgE stimulates NFAT translocation into the nucleus
Apr 1, 2004 · Our results indicate that, far from simply preparing the cells for a response to allergen, monomeric IgE can stimulate signaling pathways that lead to degranulation, …
NFAT control of innate immunity - American Society of …
Aug 16, 2012 · The calcineurin/nuclear factor of activated T cells (NFAT) signaling pathway mediates multiple adaptive T-cell functions, but recent studies have shown that …
Ligand-independent function of β2-adrenergic receptor affects IgE ...
Aug 26, 2024 · Cytokine production, Ca 2+ influx, and nuclear factor of activated T cells (NFAT) nuclear translocation were measured in Adrb2 -/- and Adrb2 +/+ BMMCs upon IgE/Ag …
Immunobiology: NFAT but not NF-κB is critical for transcriptional ...
Mar 3, 2008 · Dephosphorylation of NFAT by calcineurin enables nuclear translocation of NFAT. 32 We therefore analyzed the levels of A1 mRNA (using RPA) in BMMCs and C57 cells that …
Acting on impulse: dissecting the dynamics of the NFAT …
Jan 24, 2013 · Bottom: immunoglobulin E (IgE) mediates activation of NFAT1 and NFAT4. In response to low antigen levels, NFAT4 exhibits nuclear bursts that become sustained nuclear …
Expression of the transcription factor NFAT2 in human neutrophils: IgE ...
Jul 1, 2007 · Our results provide evidence that NFAT2 is constitutively expressed in human neutrophils, and after IgE-dependent activation operates as a transcription factor in the …
Dynamic Response Diversity of NFAT Isoforms in
Jan 24, 2013 · Next, we characterized NFAT dynamics following an immune stimulus, subjecting RBL-2H3 cells to IgE-mediated activation. We used antigen doses spanning three orders of …