NFAT - Wikipedia
Nuclear factor of activated T-cells (NFAT) is a family of transcription factors shown to be important in immune response. One or more members of the NFAT family is expressed in most cells of …
NFAT proteins: key regulators of T-cell development and function
Jun 1, 2005 · Experimental evidence indicates that, during T-cell development, calcium–calcineurin–NFAT signalling is a key regulator of positive selection. NFAT2 and …
NFAT proteins: key regulators of T-cell development and function
Since the discovery of the first nuclear factor of activated T cells (NFAT) protein more than a decade ago, the NFAT family of transcription factors has grown to include five members. It has …
Nfat: ubiquitous regulator of cell differentiation and adaptation
The nuclear factor of activated T cells (NFAT) proteins are a family of transcription factors whose activation is controlled by calcineurin, a Ca2+-dependent phosphatase. Originally identified in …
NFAT, immunity and cancer: a transcription factor comes of age
Aug 20, 2010 · Nuclear factor of activated T cells (NFAT) was first identified more than two decades ago as a major stimulation-responsive DNA-binding factor and transcriptional …
NFAT Signaling - Cell Press
Apr 19, 2002 · The four genes encoding the cytoplasmic subunits of NFAT transcription complexes play critical roles in regulating the genes necessary for interactions with cells that …
The mechanism of the NFAT transcription factor family involved in ...
Nov 3, 2022 · As a transcriptional activator widely expressed in various tissues, nuclear factor of activated T cells (NFAT) is involved in the regulation of the immune system, the development …
Transcription factors of the NFAT family: regulation and function
This review discusses recent data on the diversity of the NFAT family of transcription factors, the regulation of NFAT proteins within cells, and the cooperation of NFAT proteins with other …
Cell cycle and apoptosis regulation by NFAT transcription factors: …
The NFAT (nuclear factor of activated T cells) family of transcription factors consists of four Ca2+-regulated members (NFAT1–NFAT4), which were first described in T lymphocytes. In addition …
NFAT - an overview | ScienceDirect Topics
NFAT, short for Nuclear Factor of Activated T-cells, refers to a family of transcription factors that play a crucial role in directing specific biological processes in various cells and tissues.