1-Naphthylaminopropane (1-NAP), also known as 1-naphthylisopropylamine or as α-naphthylaminopropane (α-NAP), is a drug of the amphetamine and naphthylaminopropane families. [1] [2] [3] It is a positional isomer of 2-naphthylaminopropane (2-NAP; …

Dec 5, 2018 · Replacing the naproxen with naphthalene in Npx-1P yields Nap-1P, which hardly induces the puncta formation of COX-2 or PTP1B, further confirming the importance of the COX-2 binding moiety (i.e., naproxen).

Npx-1P, Npx-2P, Nap-1P and Npx-1 (Scheme S1) were synthesized based on reported protocols using SPPS.1 Scheme S2 shows the synthetic route of Npx-1P. The synthetic route of other compounds are the same with Npx-1P. All compounds were purified by reverse phase HPLC using HPLC grade acetonitrile and water with

Sodium phosphide is the inorganic compound with the formula Na 3 P. It is a black solid. It is often described as Na + salt of the P 3− anion. [2] . Na 3 P is a source of the highly reactive phosphide anion. It should not be confused with sodium phosphate, Na 3 PO 4.

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Our study shows that 1p and 2p, with the critical micelle concentrations (CMC) of about 54 and 60 μM, respectively, self-assemble to form nanoparticles, which turn into the nanofibers of Nap-wwy (1) or Nap-WWY (2) upon enzymatic dephophorylation catalyzed by alkaline phosphatase (ALP).

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Jan 23, 2006 · Nucleosome assembly protein 1 (NAP-1) is an integral component in the establishment, maintenance, and dynamics of eukaryotic chromatin. It shuttles histones into the nucleus, assembles nucleosomes, and promotes chromatin fluidity, thereby affecting the transcription of many genes.

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Here, we describe for the first time, the implication of NAP-1 (Nucleosome assembly protein 1), a histone chaperone that has been involved in nuclear transport, transcription regulation, and chromatin remodeling, in telomere biology.