Prolume / NanoLight has over 20 years of experience in the field of bioluminescence. If available reagents/substrates do not match your experimental setup or packaging size, we are happy to customize them for you and help you find solutions.

Since 2012 NanoLight ® has been providing non-toxic, water-soluble bioluminescent substrates mainly for the field of in vivo imaging to monitor tumor growth in mouse models.

Nanolight™ Technologies developed Prolume Purple II (US Patent 2013/057660). Prolume Purple II exhibits an up to 5-fold higher luminescence than CTZ400a (“deep blue C”). Details & Info

NanoLight Technology believes the basic researcher, drug discoverer, and agrichemical industries are only beginning to harness the power of naturally occurring bioluminescence in their research, screening, and discovery efforts.

Nanolight™ Prolume Purple exhibits an up to 13-fold higher luminescence than CTZ400a (“deep blue C”).

NanoFuel®-400a Solvent is NanoLight’s solution to the problem associated with the solubility of the highly hydrophobic Coelenterazine 400a. Coelenterazine-400a (DeepBlueC™) can be dissolved up to a concentration of 2.5 mg/ml.

Content: native Coelenterazine + non-toxic additives for water-solubility: Packaging size: 500 ug CTZ / vial in a freeze-dried form: Application: just add sterile water, vortex and use up to 500 ug CTZ in a single injection

Safety Data Sheet according to OHSA HCS 29 CFR 1910.1200(g) Trade name: Vargulin or Cypridina Luciferin Revision date: 07/29/2021 Product No: 305 Cat#305 Cypridina Luciferin CAS# 7273-34-9 www.nanolight.com Page 2 of 7 NFPA ratings (scale 0-4)

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Content h-Coelenterazine + non-toxic additives for water-solubility Packaging size: adding 10ml buffer will give a 50µM solution, adding 5 ml buffer will give a 100µM solution. Application: Just add an aequeous buffer of your choice (e.g. PBS), vortex and use for luminometer assays.