Mar 7, 2025 · Neoadjuvant chemoradiotherapy (NACRT) has long been the standard treatment for locally advanced rectal cancer (LARC), offering tumor downstaging benefits but also posing risks of radiation-induced toxicity.

This is the first meta-analysis that comprehensively compares the short- and long-term outcomes of NAC and NACRT in patients with LARC and was designed to explore the possibility of NAC replacing NACRT as the preferred option for the clinical treatment of LARC.

May 5, 2021 · Results showed that NAC was not inferior to NACRT in terms of pCR, R0 resection, local relapse, and distant metastasis, but was superior to NACRT in terms of sphincter preservation. pCR is one of the most important indexes to …

Feb 19, 2021 · Neoadjuvant chemoradiotherapy (NACRT) has been well established as the standard therapy for locally advanced rectal cancer (LARC), and is related to a survival benefit and organ preservation . The pathogenesis of colon and rectal cancer is similar. Thus, NACRT is worthy of investigation in patients with unresectable LACC.

Neoadjuvant chemoradiotherapy (NACRT) has now become the standard treatment for locally advanced rectal cancer (LARC). NACRT has decreased local relapse (LR) rate in patients with LARC; however, distant relapse has recently attracted much attention. This study aimed to assess the feasibility and efficiency of neoadjuvant chemotherapy (NAC) for ...

Kako nacrtati uvo Kako nacrtati uvo čoveka je pitanje na koje ćemo danas doneti odgovor. Kako da naučite da crtate uvo pogledaćete kroz galeriju slika po principu crtanje

This article examines the efficacy of neoadjuvant chemoradiotherapy (NACRT) versus neoadjuvant chemotherapy (NACT) in treating locally advanced EC, analyzing data from randomized controlled trials (RCTs) between 2000 and 2024.

Mar 27, 2018 · NACRT might be an alternative option for patients with LARC in the upper rectum as it has a favorable pathological complete response rate and comparable clinical outcomes when compared with patients with LARC in middle/lower rectum.

Results showed that NAC was not inferior to NACRT in terms of pCR, R0 resection, local relapse, and distant metastasis, but was superior to NACRT in terms of sphincter preservation. pCR is one of the most important indexes to evaluate the efficacy of neoadjuvant treatments.

Sep 1, 2019 · Long course neoadjuvant chemo-radiotherapy (NACRT) followed by total mesorectal excision (TME) with/without adjuvant chemotherapy (ACT) is the standard treatment modality for locally advanced rectal (T3/4; T1-4N1-2) cancers (LARC).