
NAAT Nasopharyngeal Swabs Still Gold Standard for Diagnosing …
The study authors concluded that their review of head-to-head comparisons of SARS-CoV-2 diagnostic sampling indicated NP swab NAAT remained the most effective method and that testing for COVID-19 in saliva may be the next best alternative. Reference. Lee RA, Herigon JC, Benedetti A, Pollock NR, Denkinger CM.
COVID-19 Testing: Saliva NAAT Comparable to Nasopharyngeal …
Mar 16, 2021 · The pooled nasopharyngeal swab NAAT sensitivity was 85.7% (95% CrI, 76.5-93.4) and specificity was 98.9% (95% CrI, 97.4-99.7). In studies that were conducted in ambulatory settings (n=9), the pooled saliva NAAT performance (sensitivity, 84.5%; specificity, 99.0%) remained comparable to that of the pooled nasopharyngeal swab NAAT performance ...
Antibiotic Stewardship: Role of MRSA Nasal Screening
Feb 26, 2018 · Nasal swab test MRSA nares screening can be a stewardship tool to streamline empiric antibiotic therapy among those not nares colonized with MRSA. According to the results of a study published in Clinical Infectious Diseases , nasal screening for methicillin-resistant Staphylococcus aureus (MRSA) had a high negative predictive value of 96.5% ...
Utility of MRSA-Positive Nasal Samples in Antimicrobial Stewardship
Nov 6, 2019 · Data from patients with positive result for MRSA on nasal screening upon admission or transfer were obtained from the VA Corporate Data Warehouse. Clinical cultures within 7 days of the swab of the nares were evaluated for the presence of MRSA. Sensitivity for positive MRSA clinical culture was 67.4% and specificity was 81.2%.
Are Nucleic Acid Amplification Tests Effective for Diagnosing ...
Nov 24, 2021 · Nucleic acid amplification testing (NAAT) was found to have an increased sensitivity and specificity for detecting extragenital Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections compared with standard culture methods, according to results of a study published in the Journal of Clinical Microbiology.
Challenges in Diagnosis and Treatment - Infectious Disease Advisor
Aug 21, 2017 · NAAT uses polymerase chain reaction (PCR) and can be performed on multiple sample types, including urethral, vaginal, and cervical swabs; urine; and endometrial biopsies. However, NAAT for diagnosing M genitalium uses assays that were developed for the research setting and, as a result, NAAT is only available in reference labs — usually at ...
Caution Required When Using Supplementary Nucleic Acid …
Sep 3, 2020 · Supplementary nucleic acid amplification tests (NAATs) for Neisseria gonorrhoeae should be chosen with caution to avoid discrepancies with the screening NAAT, according to a study recently published in the European Journal of Clinical Microbiology & Infectious Diseases. There are an estimated 78 million cases of gonorrhea globally each year ...
Respiratory Virus Diagnosis Guidelines Issued by ADLM
Aug 16, 2024 · The guidance notes that the preferred method for diagnosis is a NAAT, and antigen tests could be used when a NAAT is not readily available although they have lower sensitivity compared with NAATs. “DFA, serology, and viral culture are not recommended for routine diagnosis,” stated the authors.
Testing Errors, Reinfection Should be Considered When …
Jun 6, 2016 · Of the 77 patients, 5 were reported self-cleared before treatment by researchers. Ten patients had no follow up. The researchers reported a 100% cure rate for the remaining 62 patients. “Median time to clearance was 2 days, with a range of 1–7 days for RNA-based NAAT and 1–15 days for DNA-based NAAT.
RSV Detection in Adults: Paired Serology, Molecular Testing …
Aug 20, 2024 · The use of serology testing exhibited a sensitivity of 60.9% (95% CI, 46.8-75.0) when compared with any diagnostic method. The researchers also noted the addition of standard care swab results to PCR testing increased the rate of RSV detection by 25.9%.