Pue-Tan IIA significantly increased the expressions of HO-1 (1.87-fold) and NQO1 (1.76-fold) and decreased Keap1 expression (0.39-fold). The combination of Pue and Tan IIA could alleviate …

Oct 1, 2023 · Western blotting showed that the protein levels of Nrf2, HO-1, and NQO1 were significantly lower, and those of Keap1, NLRP3, Cleaved Caspase-1, and Cleaved IL-1β were …

Jan 2, 2024 · Impairment of the NQO1 activity in the CNS can result in abnormal neurotransmitter release and clearance, increased oxidative stress, and aggravated cellular injury/death. …

Jun 1, 2020 · In this study, we established mice model of middle cerebral artery occlusion/reperfusion (MCAO/R) and Neuro-2a (N2a) cell model of oxygen-glucose …

Mar 28, 2013 · We observed remarkable up-regulation of phospho-Akt and NQO1 in MCAO rats following treatment with curcumin (5 µM), and this up-regulation was accompanied by …

Jun 1, 2020 · Mice model of middle cerebral artery occlusion/reperfusion (MCAO/R) and Neuro-2a (N2a) cell model of oxygen-glucose deprivation/reoxygenation (OGD/R) were established to …

Jun 29, 2022 · Rats injected with sh-CBX7 showed higher protein expression of Nrf2 (figure 6A and B), HO-1 (figure 6A and C) and NQO1 (figure 6A and D) than the MCAO rats, revealing …

RT-qPCR results showed Nrf2 (p<0.001; Figure 4 A), NQO1 (p<0.01; Figure 4 B), GCLM (p<0.01; Figure 4 C), HO-1 (p<0.05; Figure 4 D), and GCLC (p<0.001; Figure 4 E) expression were …

建立大脑中动脉闭塞/再灌注（MCAO/R）小鼠模型和氧葡萄糖剥夺/再氧合（OGD/R）Neuro-2a（N2a）细胞模型，研究BACH1的作用。 发现 MCAO/R 小鼠在伴有严重脑梗塞的脑组织中 …

This study aimed to investigate whether RIC could reduce oxidative stress and inflammatory responses in middle cerebral artery occlusion (MCAO)-reperfusion mice via the nuclear factor …