NHLBI’s TOPMed program aims to leverage the power of artificial intelligence (AI) and machine learning (ML) to accelerate the understanding of HLBS disorders.

Precision medicine is an emerging approach to disease prevention and treatment that considers the unique genes and environment of each patient. The TOPMed program collects whole …

TOPMed genomic data and pre-existing Parent study phenotypic data are made available to the scientific community in study-specific accessions in the database of Genotypes and …

After funding whole genome sequencing of 200,000 DNA samples, TOPMed has covered many major heart, lung, blood, diseases and sleep disorders.

The TOPMed program is an important part of NHLBI’s efforts to harness data science to drive precision medicine. As part of its role in NHLBI’s broader precision medicine landscape, …

Through NHLBI’s Trans-Omics for Precision Medicine (TOPMed) program, researchers will use data from studies focused on heart, lung, blood, and sleep disorders to better predict, prevent, …

Jun 1, 2022 · This Funding Opportunity Announcement (FOA) invites applications to use NHLBI-funded TransOmics for Precision Medicine (TOPMed) program to generate a large volume of …

Feb 10, 2021 · In the first 53,831 TOPMed samples, we detected more than 400 million single-nucleotide and insertion or deletion variants after alignment with the reference genome. …

TOPMed WGS data are contained in study-specific accessions with names containing “NHLBI TOPMed,” while most phenotypic data are in parent study accessions. The TOPMed …

The National Heart, Lung and Blood Institute (NHLBI) Trans-Omics for Precision Medicine (TOPMed) program is designed to generate scientific resources to enhance understanding of …