Oligodendrocyte progenitor cells (OPCs), also known as oligodendrocyte precursor cells, NG2-glia, O2A cells, or polydendrocytes, are a subtype of glia in the central nervous system named …

Nerve/glial antigen 2 (NG2) is a chondroitin sulfate proteoglycan that in the brain occurs mostly in a class of glial cells called NG2-glia (Nishiyama et al. 2009) or in pericytes associated with …

Feb 14, 2017 · Our findings suggest that NG2 glial cells maintain neuronal function and survival via the control of neuroimmunological function. Tissue-specific stem/progenitor cell …

NG2 cells are a novel distinct class of central nervous system (CNS) glial cells, characterized by the expression of the chondroitin sulfate proteoglycan NG2. They have been detected in a …

How do they respond to injury or pathology? What is the role of neurotransmitter signaling between neurons and NG2-glia? We will first give an overview on the developmental origin of …

Dec 5, 2024 · A recent study by Liu et al. elucidated a non-cell-autonomous interaction between NG2 glia and microglia and unveiled the mechanisms underlying NG2 glia’s protection against …

May 1, 2023 · The neurovascular unit (NVU) plays a critical role in health and disease. In the current review, we discuss the critical role of a class of neural/glial antigen 2 (NG2)-expressing …

NG2-glia are a mysterious and ubiquitous glial population with a highly branched morphology. Initial studies suggested that their unique function is the generation and maintenance of …

NG2 glia is a specific glia cell type that is scattered in the brain parenchyma. Almost all of these cells are NG2+ PDGFRα + and undergo a slow rate of division, more than once a month, to …

Feb 18, 2023 · NG2 glia represents a distinct type of macroglial cells in the CNS and is unique among glia because they receive synaptic input from neurons. They are abundantly present in …