This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat NAT2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates.

Nov 10, 2016 · 要提升NAT类型，我们必须知道NAT的4个类型：NAT1、NAT2、NAT3、NAT4。 说些比较重要的前话：路由器少一层是一层，这样越有可能得到NAT1和NAT2这两类NAT类型。 这样的好处是桥接和纯AP是不进行NAT的，而是SWitch，所以不会导致多一层NAT。 此时，基本是NAT2和NAT3，正常情况对看网页、游戏及下载都没有过多的限制。 但是，现在个别网络游戏严格要求你的网络环境必须是“ NAT2 ”以上（NAT2和NAT1），才能进行游戏。 而你的网络环境又 …

Mar 30, 2025 · NAT1 (N-Acetyltransferase 1) is a Protein Coding gene. Diseases associated with NAT1 include Spina Bifida and Deafness, Autosomal Recessive 15. Among its related pathways are Metapathway biotransformation Phase I and II and Paracetamol ADME.

The two NAT enzymes in humans are NAT1 and NAT2. [4] Mice and rats express three enzymes, NAT1, NAT2, and NAT3. [4] NAT1 and NAT2 have been found to be closely related in species examined thus far, since the two enzymes share 75-95% of their amino acid sequence. [9] [10] Both also have an active site cysteine residue (Cys 68) in the N-terminal ...

Jan 14, 2025 · Rice production is facing substantial threats from global warming associated with extreme temperatures. Here we report that modifying a heat stress-induced negative regulator, a negative regulator...

Jan 4, 2025 · Title: NAT1 is a critical prognostic biomarker and inhibits proliferation of colorectal cancer through modulation of PI3K/Akt/mTOR. NAT1 genetic variation increases asthma risk in children with secondhand smoke exposure.

Jan 10, 2017 · Novel APOBEC1 target 1 (Nat1) (also known as "p97," "Dap5," and "Eif4g2") is a ubiquitously expressed cytoplasmic protein that is homologous to the C-terminal two thirds of eukaryotic translation initiation factor 4G (Eif4g1).

Arylamine N-acetyltransferase I (NAT1) is a phase II enzyme that acetylates a wide range of arylamine and hydrazine substrates. The NAT1 gene is located on chromosome 8 and shares homology to NAT genes found in most mammalian species.

NAT1*10 is the most common variant haplotype and is associated with increased risk for numerous cancers. NAT1 is transcribed from a major promoter, NATb, and an alternative promoter, NATa, resulting in messenger RNAs (mRNAs) with …

N-acetyltransferase type 1 (NAT1) catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates (summary by Butcher et al., 1998).