Mar 13, 2025 · We strive to develop first-in-class and best-in-class oral small molecule therapies for those suffering from CNS diseases. Successful CNS drugs demand a wide therapeutic margin and high CNS distribution to ensure a favorable safety profile and clinically meaningful efficacy.

Dec 30, 2018 · Myrobalan or Haritaki scientifically known as Terminalia Cebula is a typical Indian herb belonging to the plant family Combretaceae (Indian almond family). Indian Ayurvedic medicine calls Haritaki the ‘Mother of herbs’ and the ‘King of …

The common name myrobalan can refer to several unrelated fruit-bearing plant species: Myrobalan plum (Prunus cerasifera), also called cherry plum and myrobalan plum; Emblic myrobalan (Phyllanthus emblica), also called Amla and Amalaki; In the genus Terminalia: Beleric myrobalan (Terminalia bellirica), also called Bibhitaki and Belliric myrobalans

Terminalia chebula, commonly known as black-or chebulic myrobalan, [3] is a species of Terminalia, native to South Asia from Pakistan, India and Nepal east to southwest China , and south to Sri Lanka, Malaysia, and Vietnam.

Mar 18, 2025 · Myrobalan Therapeutics has been awarded a grant of more than $850,000 from the National Multiple Sclerosis Society to advance its new oral candidate MRO-002 for treating progressive forms of...

3 days ago · Myrobalan is a revered herb in traditional medicine, prized for its potent therapeutic properties and extensive health benefits. Often used in Ayurvedic formulations such as Triphala, Myrobalan (primarily Terminalia chebula) is celebrated for its ability to support digestion, detoxification, and overall vitality.

Nov 8, 2023 · What is the meaning of Myrobalan? Terminalia chebula (Chebulic Myrobalan) powder is a simple formulation made of dried ripe fruits commonly advocated as an agent in Ayurveda for improving gastrointestinal motility. Chebulic myrobalan is found to increase the percentage of gastric emptying.

Myrobalan’s brain-penetrant allosteric TYK2 inhibitor demonstrates robust suppression of inflammatory cascades with minimal off-target effects. Preliminary data reveal superior potency and exceptional blood-brain barrier penetration, while maintaining high selectivity against other Janus kinases (JAKs).

In Hinduism, the myrobalan, called the āmalaka in Sanskrit, is sacred to all three members of the Trimurti, the Hindu supreme trinity of Brahma, Vishnu, and Shiva. According to legend, during a religious gathering, Lakshmi, Vishnu's consort, expressed a desire to worship Shiva, while Parvati, Shiva's consort, wished to worship Vishnu.

Mar 17, 2025 · Myrobalan-containing remedies are described to have positive effects on metabolism, the cardiovascular system, and the immune system. The chemical composition of botanical mixtures can be very complex, and it is often impossible to identify individual compounds as specific active ingredients, which suggests a multi-target mode of action.