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Generation of a MyoD knock-in reporter mouse line to …
Herein, we report a MyoD knock-in (MyoD-KI) reporter mouse expressing tdTomato at the endogenous MyoD locus. Expression of tdTomato in MyoD-KI mice recapitulated the endogenous MyoD expression dynamics in vitro and …
Human myotube formation is determined by …
MyoD staining confirmed depletions of MyoD protein in MyoD KO myoblasts. Myosin staining showed the absence of differentiation and fusion in the MyoD …
- Author: Haifeng Zhang, Junfei Wen, Anne Bigot, Jiacheng Chen, Renjie Shang, Vincent Mouly, Pengpeng Bi
- Publish Year: 2020
Myogenic transcriptional activation of MyoD mediated …
Dec 20, 2010 · In this study, we show that HIRA is an essential factor for muscle development by establishing MyoD activation in myotubes. HIRA and Asf1a, but not CHD1 or Asf1b, mediate H3.3 incorporation in the promoter and the critical …
Identification of MyoD-Responsive Transcripts Reveals …
Jun 6, 2017 · Myogenic differentiation factor (MyoD) is a master transcription factor in muscle development and differentiation. Although several long non-coding RNAs (lncRNAs) linked to MyoD have been...
Master control: transcriptional regulation of …
Myod encodes a basic helix-loop-helix transcription factor belonging to a larger family of myogenic regulatory factors (MRFs) that together control determination and differentiation of all skeletal muscle cells.
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Comparison of Genome-Wide Binding of MyoD in Normal Human …
We have recently performed chromatin immunoprecipitation coupled to high-throughput sequencing (ChIP-seq) for the myogenic regulatory factor MyoD in murine cells of the skeletal …
MyoD induced enhancer RNA interacts with hnRNPL to activate ... - Nature
Dec 19, 2019 · By quantitative PCR (qPCR) in cells differentiating for various time points (DM −24, 0, 24, 72, and 120 h), seRNAs associated with MT stage (seRNA1-11) were indeed …
MyoD phosphorylation on multiple C terminal sites regulates …
MyoD is phosphorylated on multiple S/T-P sites in muscle differentiation. • Myogenic activity of MyoD is regulated by up to five C terminal phospho-sites. • Our optimal phospho-mutant form …
Adipose-derived small extracellular vesicle miR-146a-5p targets …
Apr 10, 2025 · RT-qPCR analysis indicated that in 90-day-old CS pigs, there was a significant down-regulation of MyoD and MyoG mRNA levels, alongside a significant up-regulation of …
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