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PubMed
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Function of the myogenic regulatory factors Myf5, MyoD
Discovery of the myogenic regulatory factor family of transcription factors MYF5, MYOD, Myogenin and MRF4 was a seminal step in understanding specification of the skeletal muscle …
- Author: Peter S. Zammit
- Publish Year: 2017
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ScienceDirect
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Function of the myogenic regulatory factors Myf5, MyoD, …
Dec 1, 2017 · Deletion of MyoD alters muscle fibre type composition towards a slower fibre type, but only in certain muscles and perturbs neuromuscular transmission. Conversely, constitutive …
- Author: Peter S. Zammit
- Publish Year: 2017
ScienceDirect
https://www.sciencedirect.com › science › article › pii
Different Pathways Regulate Expression of the Skeletal Myosin …
Nov 23, 2001 · Mammalian skeletal muscles are a mosaic of different fiber types largely defined by differential myosin heavy chain (MyHC) expression. Little is known about the molecular …
Studies of MyoD Myhc
ScienceDirect
Review Function of the myogenic regulatory factors Myf5, MyoD, Myogenin and MRF4 in skeletal muscle, satellite cells and regenerative myogenesis
Discovery of the myogenic regulatory factor family of transcription factors MYF5, MYOD, Myogenin and MRF4 was a seminal step in understanding specification of the skeletal muscle lineage and control of myogenic differentiation during development. These factors are also involved in specification of t...
Published: 2017/12/01
Keywords: Myf5; Myo…
Page Count: 14
PubMed
Activation of the beta myosin heavy chain promoter by MEF-2D, MyoD, p300, and the calcineurin/NFATc1 pathway
Calcium is a key element in intracellular signaling in skeletal muscle. Changes in intracellular calcium levels are thought to mediate the fast-to-slow transformation of muscle fiber type. One factor implicated in gene regulation in adult muscle is the nuclear factor of activated T-cells (NFAT) isof...
Author: Joachim D Mei…
Published: 2007/4
Keywords: National In…
ScienceDirect
FHL3 differentially regulates the expression of MyHC isoforms through interactions with MyoD and pCREB
In skeletal muscle, muscle fiber types are defined by four adult myosin heavy chain (MyHC) isoforms. Four and a half LIM domain protein 3 (FHL3) regulates myoblasts differentiation and gene expression by acting as a transcriptional co-activator or co-repressor. However, how FHL3 regulates MyHC expre...
Published: 2016/01/01
Cited By: 0
Keywords: MyHC myos…
PubMed
Related expression of MyoD and Myf5 with myosin heavy chain isoform types in bovine adult skeletal muscles
Skeletal muscles are characterized as fast and slow muscles, according to the expression pattern of myosin heavy chain (MyHC) isoforms in the muscle fibers. To investigate the relationships between MyHC isoforms and myogenic regulatory factors (MRFs) including MyoD, Myf5, myogenin, and MRF4 in adult...
Author: Susumu Muroya
Published: 2002/7
Keywords: National In…
National Center for Biotechnology Information
MyoD- and FoxO3-mediated hotspot interaction orchestrates super-enhancer activity during myogenic differentiation
Super-enhancers (SEs) are cis-regulatory elements enriching lineage specific key transcription factors (TFs) to form hotspots. A paucity of identification and functional dissection promoted us to investigate SEs during myoblast differentiation. ChIP-seq analysis of histone marks leads to the uncover...
Author: Xianlu L. Peng…
Published: 2017/09/09
Publication: Nucleic A…
ScienceDirect
Review Function of the myogenic regulatory factors Myf5, MyoD, Myogenin and MRF4 in skeletal muscle, satellite cells and regenerative myogenesis
Discovery of the myogenic regulatory factor family of transcription factors MYF5, MYOD, Myogenin and MRF4 was a seminal step in understanding specification of the skeletal muscle lineage and control of myogenic differentiation during development. These factors are also involved in specification of t...
Published: 2017/12/01
Cited By: 521
Page Count: 14
nih.gov
https://pmc.ncbi.nlm.nih.gov › articles
The Myogenic Regulatory Factors, Determinants of Muscle …
The Myogenic Regulatory Factors (MRFs) Myf5, MyoD, myogenin and MRF4 are members of the basic helix-loop-helix family of transcription factors that control the determination and …
Nature
https://www.nature.com › articles
Myogenin promotes myocyte fusion to balance fibre number and …
Oct 12, 2018 · Adult myog mutants display reduced muscle mass, decreased fibre size and nucleation. Adult-derived myog mutant myocytes show persistent defective fusion ex vivo. …
- Author: Massimo Ganassi, Sara Badodi, Huascar Pedro Ortuste Quiroga, Huascar Pedro Ortuste Quiroga, Peter S....
- Publish Year: 2018
Science | AAAS
https://www.science.org › doi
Human myotube formation is determined by …
Here, we report an interesting fusion model of human myoblasts where Myomaker is sufficient to induce low-grade fusion, while Myomixer boosts its …
Author: Haifeng Zhang, Junfei Wen, Anne Bigot, Jiacheng Chen, Renjie Shang, Vincent Mouly, Pengpeng Bi
Publish Year: 2020
People also ask
Why is MyoD important?
Specifically, MyoD is essential and sufficient to transactivate the fusion program. Even in the absence of other myogenic factors, MyoD induced MymX/MymK expression and robust syncytializations.
Human myotube formation is determined by MyoD
science.org
Is MyoD regulated by mir-29a-tet1 in C2C12 myoblast cells?
Chikenji, A. et al. MyoD is regulated by the miR-29a-Tet1 pathway in C2C12 myoblast cells. J Oral Sci 58, 219–29 (2016). Miller, J. B. Myogenic programs of mouse muscle cell lines: expression of myosin heavy chain isoforms, MyoD1, and myogenin.
Identification of MyoD-Responsive Transcripts Reveals a Novel ... - Nature
nature.com
Is MyoG ectopically provided in human MyoD Ko myocytes?
Expression of MyoG was abolished in human MyoD KO myocytes (Fig. 4, C and D). When MyoG was ectopically provided in MyoD KO cells, the expression of MymX and MymK genes (Fig. 4, G and H) as well as myotube formations (Fig. 4, I and J) were restored to comparable levels as achieved by MyoD rescue.
Human myotube formation is determined by MyoD
science.org
How does myhc-neo differ from developmental myhc?
In the developing human muscles, both developmental MyHC isoforms are downregulated toward the end of gestation, the corresponding MyHC transcripts are expressed at low levels at birth, and in a 1-month-old infant, MyHC-neo persists only in a few fibers (Fig. 1).
Developmental myosins: expression patterns and functional significance
skeletalmusclejournal.biomedcentral.com
Is MyoD a determinant of skeletal myogenesis?
MyoD expression marks the onset of skeletal myogenesis in myf-5 mutant mice. Development. 1994 Nov;120 (11):3083–92. doi: 10.1242/dev.120.11.3083. [DOI] [PubMed] [Google Scholar] 55. Rudnicki MA, Schnegelsberg PN, Stead RH, Braun T, Arnold HH, Jaenisch R. MyoD or myf-5 is required for the formation of skeletal muscle.
The Myogenic Regulatory Factors, Determinants of Muscle Development
pmc.ncbi.nlm.nih.gov
Is MyoD more effective than Myf5?
MyoD is strikingly more effective than Myf5 at inducing differentiation-phase target genes than Myf5, whereas both MyoD and Myf5 control relatively the same type of genes related to cell proliferation (75, 76).
The Myogenic Regulatory Factors, Determinants of Muscle Development
pmc.ncbi.nlm.nih.gov
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nih.gov
https://pmc.ncbi.nlm.nih.gov › articles
MyoD-expressing progenitors are essential for skeletal …
Using MyoDiCre mice, we show that DTA-mediated ablation of MyoD-expressing cells results in the cessation of myogenesis by embryonic day 12.5 (E12.5), as assayed by myosin heavy chain (MyHC) and Myogenin staining.
Skeletal Muscle
https://skeletalmusclejournal.biomedcentral.com › articles
Developmental myosins: expression patterns and functional …
Jul 15, 2015 · Embryonic and neonatal myosins have been especially well characterized in developing rat and mouse skeletal muscles. MyHC-emb and MyHC-neo transcripts have been …
PubMed
https://pubmed.ncbi.nlm.nih.gov
Activation of the beta myosin heavy chain promoter by MEF-2D, …
Along with NFATc1, myocyte enhancer factor-2D (MEF-2D) and the myogenic transcription factor MyoD transactivated the MyHCbeta promoter in calcium-ionophore-treated myotubes in a …
Nature
https://www.nature.com › articles
Identification of MyoD-Responsive Transcripts Reveals …
Jun 6, 2017 · MyoD knockout mice displayed a dramatic loss of myosin heavy chain (MyHC) protein, a hallmark of fibre formation 6, furthermore, these mice showed disturbed neuromuscular junctions, an...
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Function of the myogenic regulatory factors Myf5, MyoD

Function of the myogenic regulatory factors Myf5, MyoD, …

Different Pathways Regulate Expression of the Skeletal Myosin …

The Myogenic Regulatory Factors, Determinants of Muscle …

Myogenin promotes myocyte fusion to balance fibre number and …

Human myotube formation is determined by …

Human myotube formation is determined by MyoD

Identification of MyoD-Responsive Transcripts Reveals a Novel ... - Nature

Human myotube formation is determined by MyoD

Developmental myosins: expression patterns and functional significance

The Myogenic Regulatory Factors, Determinants of Muscle Development

The Myogenic Regulatory Factors, Determinants of Muscle Development

MyoD-expressing progenitors are essential for skeletal …

Developmental myosins: expression patterns and functional …

Activation of the beta myosin heavy chain promoter by MEF-2D, …

Identification of MyoD-Responsive Transcripts Reveals …

Related searches for MyoD Myhc

Related searches for MyoD Myhc