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MyoD - Wikipedia
MyoD is one of the earliest markers of myogenic commitment. MyoD is expressed at extremely low and essentially undetectable levels in quiescent satellite cells, but expression of MyoD is activated in response to exercise or muscle tissue damage. See more
MyoD, also known as myoblast determination protein 1, is a protein in animals that plays a major role in regulating muscle differentiation. MyoD, which was discovered in the laboratory of Harold M. Weintraub, … See more
MyoD is a transcription factor and can also direct chromatin remodelling through binding to a DNA motif known as the E-box. MyoD is known to have binding interactions with … See more
MyoD has been shown to interact with:
• C-jun,
• CREB-binding protein,
• See moreMyoD was cloned by a functional assay for muscle formation reported in Cell in 1987 by Davis, Weintraub, and Lassar. It was first described as a nuclear phosphoprotein in … See more
Wikipedia text under CC-BY-SA license MyoD is a 3D genome structure organizer for muscle cell identity
Jan 11, 2022 · We show that MyoD functions as a “genome organizer” that specifies 3D genome architecture unique to muscle cell development, and that H3K27ac is insufficient for the …
MyoD, a Lesson in Widespread DNA Binding - Cell Press
Apr 20, 2010 · MyoD is a classic master regulator that commits those somite cells in which it is expressed to a myoblast fate and also later activates skeletal muscle genes during the …
- Author: Mark D. Biggin
- Publish Year: 2010
Function of the myogenic regulatory factors Myf5, MyoD
Discovery of the myogenic regulatory factor family of transcription factors MYF5, MYOD, Myogenin and MRF4 was a seminal step in understanding specification of the skeletal muscle …
- Author: Peter S. Zammit
- Publish Year: 2017
MyoD is functionally linked to the silencing of a muscle-specific ...
In this work, we show by chromatin immunoprecipitation (ChIP) assays that MyoD and HDAC1 are both occupying the promoter of myogenin and that this gene is in a region of repressed …
MyoD-Induced Trans-Differentiation: A Paradigm for Dissecting …
The discovery of the skeletal muscle-specific transcription factor MyoD represents a milestone in the field of transcriptional regulation during differentiation and cell-fate reprogramming. MyoD …
Selective androgen receptor modulator, YK11, regulates myogenic ...
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces …
MyoD - wikidoc
MyoD is one of the earliest markers of myogenic commitment. MyoD is expressed at extremely low and essentially undetectable levels in quiescent satellite cells, but expression of MyoD is …
Molecular expression of myostatin and MyoD is …
May 1, 2001 · Expression of myogenin peaked later than MyoD (P< 0.05); however, it did not differ between NM and DM. These data show that myostatin and MyoD increase coincidentally during formation of muscle fibers, indicating …
Master control: transcriptional regulation of mammalian Myod
More than 20 years ago, studies established that Myod expression is largely controlled by just two enhancer regions located within a region 24 kb upstream of the transcription start site in …
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